All Boards >> Irritable Bowel Syndrome Research Library

View all threads Posts     Flat     Threaded

Constipation and Risk of Cardiovascular Disease among Postmenopausal Women
      08/03/11 03:58 PM
HeatherAdministrator

Reged: 12/09/02
Posts: 7790
Loc: Seattle, WA

Constipation and Risk of Cardiovascular Disease among Postmenopausal Women

Elena Salmoirago-Blotcher, MDemail address
,
Sybil Crawford, PhD
,
Elizabeth Jackson, MD
,
Judith Ockene, PhD
,
Ira Ockene, MD

published online 10 June 2011.



Background

Constipation is common in Western societies, accounting for 2.5 million physician visits/year in the US. Because many factors predisposing to constipation also are risk factors for cardiovascular disease, we hypothesized that constipation may be associated with increased risk of cardiovascular events.
Methods

We conducted a secondary analysis in 93,676 women enrolled in the observational arm of the Women's Health Initiative. Constipation was evaluated at baseline by a self-administered questionnaire. Estimates of the risk of cardiovascular events (cumulative end point including mortality from coronary heart disease, myocardial infarction, angina, coronary revascularization, stroke, and transient ischemic attack) were derived from Cox proportional hazards models adjusted for demographics, risk factors, and other clinical variables (median follow-up 6.9 years).
Results

The analysis included 73,047 women. Constipation was associated with increased age, African American and Hispanic descent, smoking, diabetes, high cholesterol, family history of myocardial infarction, hypertension, obesity, lower physical activity levels, lower fiber intake, and depression. Women with moderate and severe constipation experienced more cardiovascular events (14.2 and 19.1 events/1000 person-years, respectively) compared with women with no constipation (9.6/1000 person-years). After adjustment for demographics, risk factors, dietary factors, medications, frailty, and other psychological variables, constipation was no longer associated with an increased risk of cardiovascular events except for the severe constipation group, which had a 23% higher risk of cardiovascular events.
Conclusion

In postmenopausal women, constipation is a marker for cardiovascular risk factors and increased cardiovascular risk. Because constipation is easily assessed, it may be a helpful tool to identify women with increased cardiovascular risk.

http://www.amjmed.com/article/PIIS0002934311002920/abstract?rss=yes

--------------------
Heather is the Administrator of the IBS Message Boards. She is the author of Eating for IBS and The First Year: IBS, and the CEO of Heather's Tummy Care. Join her IBS Newsletter. Meet Heather on Facebook!

Print     Remind Me     Notify Moderator    

Entire thread
* Gender / Hormones
HeatherAdministrator
07/14/03 01:57 PM
* Pain management in women is often overlooked and ineffective
HeatherAdministrator
02/16/15 04:42 PM
* Women, Hormones and IBS
HeatherAdministrator
03/11/14 02:09 PM
* Fennel is an effective herbal drug for menstrual pain
HeatherAdministrator
08/27/13 11:29 AM
* Constipation and Risk of Cardiovascular Disease among Postmenopausal Women
HeatherAdministrator
08/03/11 03:58 PM
* Differences in Gastrointestinal Symptoms According to Gender in Rome II Positive IBS and Dyspepsia
HeatherAdministrator
03/11/10 01:51 PM
* Gender-related differences in prepulse inhibition of startle in irritable bowel syndrome
HeatherAdministrator
03/11/10 01:48 PM
* No evidence of sex differences in heritability of irritable bowel syndrome
HeatherAdministrator
03/31/08 11:36 AM
* Acupuncture for the treatment of pain from a gender perspective.
HeatherAdministrator
03/31/08 11:27 AM
* The menstrual cycle and its effect on inflammatory bowel disease and irritable bowel syndrome
HeatherAdministrator
11/07/07 02:35 PM
* Irritable Bowel Syndrome Is More Common in Women Regardless of the Menstrual Phase
HeatherAdministrator
11/07/07 02:31 PM
* Pelvic floor dysfunction and IBS in patients with interstitial cystitis.
HeatherAdministrator
10/10/07 12:33 PM
* Women with IBS have abnormal pain modulation
HeatherAdministrator
10/10/07 12:01 PM
* Anxiety or Depression with IBS Affects More Women Than Men
HeatherAdministrator
09/24/07 11:31 AM
* Colonoscopies more difficult and painful for women and people with IBS
HeatherAdministrator
09/24/07 11:22 AM
* Role of gender and early childhood in constipation
HeatherAdministrator
09/13/07 11:09 AM
* Changes in Bowel Function: Pregnancy and the Puerperium
HeatherAdministrator
03/01/07 01:39 PM
* Drugs for gastrointestinal disorders in pregnant women.
HeatherAdministrator
05/13/06 03:20 PM
* Functional bowel disorders in patients with pelvic organ prolapse and incontinence
HeatherAdministrator
12/08/05 12:10 PM
* Sex specific alterations in autonomic function among patients with irritable bowel syndrome
HeatherAdministrator
11/12/05 01:16 PM
* Women With Interstitial Cystitis at Risk for Irritable Bowel Syndrome and Depression
HeatherAdministrator
09/22/05 04:39 PM
* Women and Men Perceive Pain Differently
HeatherAdministrator
09/13/05 12:55 PM
* Overlapping Conditions in Women With Irritable Bowel Syndrome
HeatherAdministrator
04/24/05 03:58 PM
* Bowel habit in irritable bowel syndrome in women: Defining an alternator
HeatherAdministrator
04/10/05 06:18 PM
* Recognition and treatment of irritable bowel syndrome among women with chronic pelvic pain
HeatherAdministrator
03/28/05 12:18 PM
* Irritable bowel syndrome, chronic pelvic inflammatory disease and endometriosis
HeatherAdministrator
02/19/05 05:43 PM
* A gene for diarrhoea-predominant IBS in women?
HeatherAdministrator
11/28/04 02:21 PM
* Autonomic Cardiovascular Responses Are Impaired in Women With Irritable Bowel Syndrome
HeatherAdministrator
09/12/04 03:41 PM
* Abdominal Bloating: Relation to Rectal Hypersensitivity and Menstrual Cycle
HeatherAdministrator
06/27/04 01:55 PM
* Catching Colon Cancer in Women Can Be Tough
HeatherAdministrator
04/13/04 03:32 PM
* Women More Sensitive to Pain Than Men
HeatherAdministrator
04/13/04 03:31 PM
* Gender Differences In Brain Response To IBS Pain
HeatherAdministrator
11/18/03 03:32 PM
* After Menopause, IBS Lessens in Women
HeatherAdministrator
11/04/03 03:34 PM
* Is hormone replacement therapy associated with an increased risk of irritable bowel syndrome?
HeatherAdministrator
07/25/03 11:43 AM
* Sleep disturbance influences gastrointestinal symptoms in women with irritable bowel syndrome.
HeatherAdministrator
07/18/03 01:00 PM
* Symptoms across the menstrual cycle in women with irritable bowel syndrome.
HeatherAdministrator
07/18/03 12:58 PM
* Does a physically active lifestyle improve symptoms in women with irritable bowel syndrome?
HeatherAdministrator
07/18/03 12:54 PM
* Relation between hysterectomy and the irritable bowel
HeatherAdministrator
07/18/03 11:48 AM
* Diagnosis and management of IBS, constipation, and diarrhea in pregnancy.
HeatherAdministrator
07/18/03 11:47 AM
* Physician perception of IBS management in women and men.
HeatherAdministrator
07/15/03 06:38 PM
* Gender issues in the management of IBD and IBS
HeatherAdministrator
07/15/03 06:11 PM
* Gender differences in gut transit
HeatherAdministrator
07/15/03 06:07 PM
* Bowel dysfunction in postmenopausal women.
HeatherAdministrator
07/15/03 06:04 PM
* Irritable Bowel Syndrome Worse During Periods
HeatherAdministrator
07/14/03 03:25 PM
* Sex-related differences in IBS patients: Central processing of visceral stimuli
HeatherAdministrator
07/14/03 02:40 PM

Extra information
0 registered and 31 anonymous users are browsing this forum.

Moderator:  Heather 



Permissions
      You cannot post until you login
      You cannot reply until you login
      HTML is enabled
      UBBCode is enabled

Thread views: 176827

Jump to

| Privacy statement Help for IBS Home

*
UBB.threads™ 6.2


McAfee SECURE sites help keep you safe from identity theft, credit card fraud, spyware, spam, viruses and online scams

HelpForIBS.com BBB Business Review