All Boards >> Irritable Bowel Syndrome Research Library

View all threads Posts     Flat     Threaded

Stress, the Brain-Gut Axis, and IBS
      07/17/07 11:34 AM
HeatherAdministrator

Reged: 12/09/02
Posts: 7799
Loc: Seattle, WA

Stress and the Emotional Motor System (EMS)
eCAM Advance Access published online on May 17, 2007
eCAM, doi:10.1093/ecam/nem046

Min/Body Psychological Treatments for Irritable Bowel Syndrome
Bruce D. Naliboff1,2,3, Michael P. Fresé1,2,3 and Lobsang Rapgay2
1UCLA Center for Neurovisceral Sciences and Women's Health, 2Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine at UCLA and 3Veterans Administration Greater Los Angeles Healthcare System, Los Angeles, CA, USA




A variety of experimental and clinical studies support the model described above. In general, IBS patients show altered perception of visceral events that is characterized by hypervigilance, hypersensitivity and increased autonomic arousal (16,17). While peripheral GI factors may play a role in subsets of patients with IBS (e.g. post-infectious IBS), there is converging clinical and neurobiologic research to suggest that enhanced central stress responsiveness involving anxiety may provide a specific mechanism for enhanced visceral sensitivity found in these disorders (11). GI symptom-specific anxiety may be an especially important variable leading to increased pain sensitivity, hypervigilance and poor coping (18,19). Mild psychologic stress increases visceral perception in IBS patients but not in healthy controls (20) and IBS symptoms are exacerbated following stressful life events (21). We have also recently shown that visceral-specific anxiety appears to be particularly important in IBS and may be the primary element in mediating the impact between changes in symptom severity and changes in quality of life in IBS sufferers (18). Recent brain imaging findings have now begun to show the central circuitry that may underlie many of the observations described above (22). For example, patients with IBS during visceral stimulation show increased activation in the anterior cingulate cortex, a brain region involved in vigilance and discomfort during physical and social situations (23).

http://ecam.oxfordjournals.org/cgi/content/full/nem046v1#SEC3



--------------------
Heather is the Administrator of the IBS Message Boards. She is the author of Eating for IBS and The First Year: IBS, and the CEO of Heather's Tummy Care. Join her IBS Newsletter. Meet Heather on Facebook!

Print     Remind Me     Notify Moderator    

Entire thread
* Brain-Gut
HeatherAdministrator
07/14/03 01:59 PM
* There’s a ‘second brain’ in your gut — and it’s smarter than you think
HeatherAdministrator
07/07/17 04:46 PM
* Gut bacteria may play a role in regulating myelination in the brain's prefrontal cortex
HeatherAdministrator
10/26/15 03:04 PM
* Perceived stress higher among patients with IBS
HeatherAdministrator
09/08/15 03:08 PM
* How the Gut's Second Brain Influences Mood and Well-Being
HeatherAdministrator
07/15/14 03:08 PM
* Does bacteria connect the brain and the gut?
HeatherAdministrator
09/27/13 11:44 AM
* Women With IBS Show Changes In Their Brains
HeatherAdministrator
07/28/10 11:01 AM
* Brain-gut axis dysfunction in IBS
HeatherAdministrator
03/16/10 11:27 AM
* Olfactory and gustatory function in irritable bowel syndrome
HeatherAdministrator
03/16/10 11:24 AM
* Mind/Body psychological treatments for irritable bowel syndrome
HeatherAdministrator
03/18/09 05:47 PM
* Women With IBS Can't Switch Off Pain Response
HeatherAdministrator
01/18/08 12:39 PM
* Daily stress and gastrointestinal symptoms in women with irritable bowel syndrome
HeatherAdministrator
12/06/07 04:41 PM
* Colonic Hypersensitivity in IBS - Brain or Gut?
HeatherAdministrator
09/13/07 12:04 PM
* Stress, the Brain-Gut Axis, and IBS
HeatherAdministrator
07/17/07 11:34 AM
* The Effectiveness of Hypnotherapy in the Management of Irritable Bowel Syndrome
HeatherAdministrator
10/26/06 10:16 AM
* An international study of irritable bowel syndrome: Family relationships and mind-body attributions
HeatherAdministrator
06/04/06 12:28 PM
* A Neurobiology of Sensitivity?
HeatherAdministrator
06/04/06 12:16 PM
* Pathophysiology of IBS and Serotonin Signaling
HeatherAdministrator
07/05/05 03:22 PM
* Serotonin receptors and transporters — roles in normal and abnormal gastrointestinal motility
HeatherAdministrator
11/08/04 04:38 PM
* Alterations of sensori-motor functions of the digestive tract in the pathophysiology of IBS
HeatherAdministrator
09/12/04 03:44 PM
* Visceral Sensitivity Index: Development and Validation of a GI Symptom-Specific Anxiety Scale
HeatherAdministrator
07/24/04 01:54 PM
* Brain activity during distention of the descending colon in humans
HeatherAdministrator
07/11/04 02:07 PM
* Irritable bowel syndrome: a model of the brain-gut interactions
HeatherAdministrator
05/25/04 12:28 PM
* The human enteric nervous system
HeatherAdministrator
05/11/04 07:10 PM
* Images Show a Snub Really Is Like Kick in the Gut
HeatherAdministrator
10/20/03 03:43 PM
* The Brain-Gut Connection
HeatherAdministrator
09/01/03 11:43 AM
* The Neurobiology of Stress and Emotions, and IBS
HeatherAdministrator
07/23/03 10:35 AM
* Gut Feelings: The Surprising Link Between Mood and Digestion
HeatherAdministrator
07/23/03 10:31 AM
* Sleep and gastric function in irritable bowel syndrome: derailing the brain-gut axis
HeatherAdministrator
07/18/03 12:42 PM
* The autonomic nervous system in functional bowel disorders.
HeatherAdministrator
07/18/03 12:40 PM
* Regional cerebral activation in irritable bowel syndrome
HeatherAdministrator
07/18/03 12:36 PM
* Intestinal reactivity to words with emotional content and brain information processing in IBS
HeatherAdministrator
07/18/03 12:35 PM
* Perceptual hyperreactivity to auditory stimuli in patients with irritable bowel syndrome.
HeatherAdministrator
07/18/03 12:33 PM
* The gut as a neurological organ.
HeatherAdministrator
07/18/03 12:28 PM
* Brain research in functional gastrointestinal disorders.
HeatherAdministrator
07/18/03 12:24 PM
* The gut has a mind of its own
HeatherAdministrator
07/14/03 04:07 PM

Extra information
0 registered and 1 anonymous users are browsing this forum.

Moderator:  Heather 



Permissions
      You cannot post until you login
      You cannot reply until you login
      HTML is enabled
      UBBCode is enabled

Thread views: 223861

Jump to

| Privacy statement Help for IBS Home

*
UBB.threads™ 6.2


HelpForIBS.com BBB Business Review