All Boards >> Irritable Bowel Syndrome Research Library

View all threads Posts     Flat     Threaded

Cannabinoids Show Promise for Inflammatory Bowel Disease
      09/01/05 11:23 AM
HeatherAdministrator

Reged: 12/09/02
Posts: 7799
Loc: Seattle, WA

Cannabinoids Show Promise for Inflammatory Bowel Disease

NEW YORK (Reuters Health) Aug 12 - Cannabis-based drugs may have therapeutic potential in inflammatory bowel disease, UK researchers report in the August issue of Gastroenterology.

"The system that responds to cannabis in the brain is present and functioning in the lining of the gut," lead researcher Dr. Karen Wright, of the University of Bath, explained to Reuters Health. "There is an increased presence of one component of this system during inflammatory bowel diseases -- Crohn's and ulcerative colitis."

Dr. Wright and her colleagues established the location of cannabinoid receptors CB1 and CB2 in human colonic tissue and used human colonic epithelial cells lines in cannabinoid-binding and in wound-healing experiments.

Expression of both receptors was detected on plasma cells in the lamina propria, but only CB2 was present on macrophages.

CB2 was increased and immunoreactivity was seen in the epithelium of colonic tissue characteristic of inflammatory bowel disease. Cannabinoids enhanced epithelial wound closure via CB1-related mechanisms.

Thus continued Dr. Wright, "cannabinoids, which we make ourselves, as well as synthetic cannabinoids, can promote wound healing in the gut, which is extremely interesting given that inflammatory bowel disease involves damaged gut linings."

Although no data are available yet, she added, relevant case studies of the use of cannabinoids are taking place in the UK and a clinical trial is being conducted in Germany.

Gastroenterology 2005.


http://www.medscape.com/viewarticle/510626?src=mp

--------------------
Heather is the Administrator of the IBS Message Boards. She is the author of Eating for IBS and The First Year: IBS, and the CEO of Heather's Tummy Care. Join her IBS Newsletter. Meet Heather on Facebook!

Print     Remind Me     Notify Moderator    

Entire thread
* Inflammatory Bowel Disease
HeatherAdministrator
07/14/03 01:51 PM
* Why cannabis relieves IBD symptoms
HeatherAdministrator
08/22/18 02:39 PM
* Dietary fiber associated with reduced Crohn's disease flares
HeatherAdministrator
01/27/16 02:58 PM
* Probiotics not superior for maintaining ulcerative colitis remission
HeatherAdministrator
12/29/15 10:12 AM
* Fecal transplant induces remission in active ulcerative colitis
HeatherAdministrator
07/16/15 04:39 PM
* 7 recent developments in Crohn's disease
HeatherAdministrator
04/02/15 03:16 PM
* Hormonal contraception improved menstrual-related IBD symptoms
HeatherAdministrator
09/15/14 12:43 PM
* Fecal lactoferrin differentiated IBD from IBS
HeatherAdministrator
07/29/14 01:50 PM
* Vitamin D and Cancer Risk in IBD
HeatherAdministrator
07/15/14 02:53 PM
* Self-assessment scale developed for patients with IBD-fatigue
HeatherAdministrator
06/17/14 10:44 AM
* Stool test distinguishes between IBD and IBS
HeatherAdministrator
04/07/14 01:40 PM
* Breathing exercises, meditation improved inflammatory markers, quality of life in IBD patients
HeatherAdministrator
10/23/13 04:20 PM
* Inflammatory Bowel Disease: Heat Waves Linked to Flares
HeatherAdministrator
08/16/13 12:58 PM
* Dietary changes may reduce effects of IBD
HeatherAdministrator
06/27/13 05:43 PM
* Genetic Clues May Help Unravel Cause of Crohn's
HeatherAdministrator
11/02/12 12:59 PM
* Inflammatory bowel, ulcerative colitis linked to intestinal fungi
HeatherAdministrator
06/15/12 01:23 PM
* Smoking makes Crohn's disease worse
HeatherAdministrator
05/09/12 01:33 PM
* Kids With Crohn’s Disease, Colitis Often Struggle at School
HeatherAdministrator
04/23/12 01:22 PM
* As Nations Develop, So May Bowel Disease
HeatherAdministrator
01/09/12 12:01 PM
* Loneliness Triggers Inflammatory Illnesses
HeatherAdministrator
02/10/11 10:05 AM
* Infants' antibiotic use tied to IBD risk
HeatherAdministrator
11/03/10 01:42 PM
* Olive Oil May Protect Against Ulcerative Colitis
HeatherAdministrator
05/05/10 10:32 AM
* Accutane may cause ulcerative colitis
HeatherAdministrator
04/09/10 01:38 PM
* Red meat may raise odds for ulcerative colitis, but oily fish could be protective
HeatherAdministrator
03/11/10 01:22 PM
* Inflammatory Bowel Disease and Irritable Bowel Syndrome: Separate or Unified?
HeatherAdministrator
01/05/10 12:03 PM
* Novel Compound Targets Mucosal Healing in Crohn's
HeatherAdministrator
05/29/06 02:19 PM
* Viagra May Help Crohn's Disease
HeatherAdministrator
03/04/06 12:50 PM
* Carbon Monoxide Eases Ulcerative Colitis
HeatherAdministrator
01/18/06 04:12 PM
* Colonoscopic Surveillance in Inflammatory Bowel Disease
HeatherAdministrator
10/11/05 01:33 PM
* Oral Contraceptives and HRT a Risk Factor for Inflammatory Bowel Disease
HeatherAdministrator
09/13/05 01:22 PM
* Cannabinoids Show Promise for Inflammatory Bowel Disease
HeatherAdministrator
09/01/05 11:23 AM
* Differentiation of Inflammatory Bowel Disease and Irritable Bowel Syndrome
HeatherAdministrator
09/01/05 11:13 AM
* The Clinical Epidemiology of Inflammatory Bowel Disease
HeatherAdministrator
08/22/05 04:45 PM
* IBD Patients May Benefit From Folic Acid Supplementation
HeatherAdministrator
05/22/05 07:02 PM
* Fish oil, soluble fiber, and antioxidants for corticosteroid sparing in ulcerative colitis
HeatherAdministrator
04/24/05 03:33 PM
* Biotic Therapy Cuts Inflammation in Ulcerative Colitis
HeatherAdministrator
02/19/05 05:59 PM
* Calming Crohn's Disease with Fish Oil and Antioxidants
HeatherAdministrator
01/07/05 04:55 PM
* Probiotics Prove Just As Effective As a Popular Prescription Drug for Ulcerative Colitis
HeatherAdministrator
12/20/04 01:37 PM
* Increased Incidence of Inflammatory Bowel Disease: The Price of the Decline of Infectious Burden?
HeatherAdministrator
11/28/04 02:58 PM
* Diet May Influence Relapse in Ulcerative Colitis
HeatherAdministrator
10/24/04 07:50 PM
* Parasite Therapy for Crohn's and Colitis?
HeatherAdministrator
08/08/04 03:00 PM
* Pipeline Treatments, Novel Procedures Offer New Options for GI Diseases
HeatherAdministrator
06/04/04 06:41 PM
* Faulty Gene for Crohn's Disease Found
HeatherAdministrator
04/13/04 03:19 PM
* Data links Crohn's disease and antibiotics
HeatherAdministrator
02/24/04 02:07 PM
* Elan Reports Successful Results of Antegren Trial for Crohn's Disease
HeatherAdministrator
02/10/04 01:30 PM
* 5-ASA Therapy for Inflammatory Bowel Disease No Bar to Colon Cancer
HeatherAdministrator
02/10/04 01:29 PM
* Once-Daily Probiotic Treatment Maintains Remission in Ulcerative Colitis patients with Pouchitis
HeatherAdministrator
01/26/04 03:33 PM
* Bone Disease and Intestinal Problems May Share a Common Cause
HeatherAdministrator
01/07/04 11:47 AM
* Increased Anal Resting Pressure and Rectal Sensitivity in Crohn's Disease
HeatherAdministrator
12/16/03 11:59 AM
* Environmental Factors May Play a Role in the Pathogenesis of IBD
HeatherAdministrator
12/01/03 05:56 PM
* Colonoscopy Prep
HeatherAdministrator
10/17/03 12:05 PM
* Detection of Pulmonary Involvement in Inflammatory Bowel Disease
HeatherAdministrator
09/30/03 01:20 PM
* Indeterminate Colitis
HeatherAdministrator
09/16/03 03:33 PM
* Familial Occurrence of Inflammatory Bowel Disease in Celiac Disease
HeatherAdministrator
09/16/03 03:30 PM
* Bacteria in Milk Linked to Crohn's Disease and Possibly IBS
HeatherAdministrator
08/12/03 11:55 AM
* Inflammatory Bowel Disease During Pregnancy.
HeatherAdministrator
07/15/03 06:20 PM
* A study of the menopause, smoking, and contraception in women with Crohn's disease.
HeatherAdministrator
07/15/03 06:05 PM
* Hormone replacement therapy prevents bone loss in patients with IBD
HeatherAdministrator
07/15/03 06:02 PM
* Chemo Drug Improves Crohn's Symptoms
HeatherAdministrator
07/14/03 04:09 PM

Extra information
0 registered and 3 anonymous users are browsing this forum.

Moderator:  Heather 



Permissions
      You cannot post until you login
      You cannot reply until you login
      HTML is enabled
      UBBCode is enabled

Thread views: 338607

Jump to

| Privacy statement Help for IBS Home

*
UBB.threads™ 6.2


HelpForIBS.com BBB Business Review