Hello -

Why are women more likely than men to suffer from IBS, fibromyalgia, osteoarthritis, and other chronic pain conditions?

There's a brand new theory that could radically change how men and women are treated for pain.

In a groundbreaking study just published in the journal BRAIN, researchers at University of Arizona Health Sciences identified two substances - prolactin and orexin B - that appear to make mice, monkeys and humans more sensitized to pain.

Prolactin is a hormone that promotes breast development and lactation in females. Orexin B is a neurotransmitter that helps keep us awake and stimulates appetite.

Both males and females have prolactin and orexin, but females have much higher levels of prolaction and males have more orexin.

In addition to promoting lactation and wakefulness, both substances also appear to play a role in regulating nociceptors, specialized nerve cells near the spinal cord that produce pain when they are activated by a disease or injury.

This is huge news!

It means that the basic, underlying mechanisms that result in the perception of pain are different in males and females. And there are actually distinctive "male" and "female" nociceptors.

You are not alone!

P.S. If you have questions or comments I'd love to hear them - just reply to this email to reach me directly. I am overwhelmed with requests but try to answer everyone. For help today please join my private IBS coaching.

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Heather Van Vorous
Heather Van Vorous
Over 40 years dealing with IBS
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