Hello -

This is a technical but fascinating new research study on IBS. Stay with me...

1. IBS is one of the most common functional bowel disorders.

2. Dysmetabolism - basically dysfunctional metabolism - plays an important role in the pathogenesis of diseases. It may play a role in IBS as well.

3. There is a lack of information regarding the causal relationship between circulating metabolites and IBS.

4. So this study evaluated the causal relationship between genetically proxied 486 blood metabolites and IBS.

In a nutshell, the underlying mechanisms of IBS remain poorly understood. Research is ongoing in the areas of gastrointestinal motility, visceral hypersensitivity, intestinal secretion and intestinal permeability.

Genome studies have identified numerous genetic variations that make people vulnerable to IBS. This offers molecular insights into the complex interplay between environmental and genetic factors in the development of IBS.

Increasing evidence shows an altered metabolic profile in either the host or the gut microbiota, as well as their interactions, likely play a significant role in the manifestation of IBS symptoms.

This study suggests that the metabolites implicated in the development of IBS have potential as biomarkers. This could help illuminate the underlying biological mechanisms of this condition, which could lead to new treatments.

More about current IBS treatments.

You are not alone!

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Heather Van Vorous
Heather Van Vorous
Over 40 years dealing with IBS
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