Hi,i take colofac,i'v been on it for two months,i am ibs (c) It made a great difference to my spasms,i also had bladder spasms.All that i can say is that at first i had headaches and at times dry nose and mouth,i think this is a side effect to mebeverine that is in colofac,the headaches have stopped.I don't know about the long term effects to this i myself feel that i would not like to have to take antispasmodics long term,actually since starting soluable food i only take one here and there because my (c) is very normal now and that is where most of my pain came from. Ask medical advice if you are worried,sorry i can't be more helpful,good luck with this. Tina.
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