The relationship between fibromyalgia and IBS goes the other way too. A study of a random sample of 27,402 people drawn from 97,593 individuals with IBS showed individuals with IBS have a 40% to 80% higher prevalence odds of migraine, fibromyalgia, and depression. Both the brain-gut mechanism and fibromyalgia involve the HPA axis (hypothalamo-pituitary-adrenal axis) which may be responsible for the overlap between these two disorders. It need not be psychological.
-------------------- STABLE: ♂, IBS-D 50+ years - Science of IBS
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