My heart is bleeding for you. I'm fairly new to the boards but have been following your painful journey with much admiration. I hope the methotrexate will relieve your symptoms and be gentle on your body. If is so frightening to read the list of possible side effects that one may experience with certain medications and so difficult to make those treatment decisions. I just recently turned down botox injections in my neck (for neck pain) after reading all the patient disclosure papers I had to sign (more like doctor protection papers). I decided to get a second opinion and may still get the treatment but not until I'm convinced that it is the way to go. As with anything you have to weigh the risks and benefits. Sounds like you have done your research and are making a good decision based on experience and knowledge.
By the way, the pics you posted of "the boys" are just adorable. There's a lot of love in those two little fur bundles.