I don't care what it has in it as long as it kills the nausea. It can trigger the worst IBS attack in the world.....as long as I'm not nauseated, I'd live through it. When I'm having an attack AND I'm nauseated.....forget it.....I just want to die!!! I'm still going to try it. If it doesn't trigger IBS attacks in Kate, who is really bad IBS-D, then I think I'm safe. BUT, antihistimines, in general, always upset my stomach. Maybe they put the lactose in it to help with the stomach upset. ???