Re: Zelnorm,Lotronex and Gender
04/26/03 08:28 PM
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jrs
Reged: 03/31/03
Posts: 317
Loc: Aberystwyth, Wales
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I'm pretty sure that they tested Lotronex on both men and women, but the effect was only statistically significant in women. This didn't stop the doctors from prescribing it to everyone though, which (probably in part) caused the situation where it was withdrawn from the market.
Personally, I'm waiting for Cilansetron to come to the market, assuming that the Phase III trials go well. It's a 5HT3-antagonist like Lotronex, but (so far) doesn't seem to exhibit the same side effects, which, may I add, were potentially pretty nasty -- my mom's a nurse and I asked her to describe what they were in real terms -- IBS is definitely better than having an adverse reaction to Lotronex!
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