Irritable Bowel Syndrome Message Boards

I sure hope politics does not play a big role in determining if a drug gets FDA approval. It would be a shame.

Please direct me to a clinical trial of long term use of the antibiotic Rifaxamin that shows it is benign? It may have minimal side effects in short term use but to the best of my knowledge that are no long term studies on the effect of prolonged use as stated in the editorial about the Rifaxamin study that say "studies that will assess the longer-term effect of rifaximin treatment are eagerly awaited. Until this information becomes available, it seems prudent to restrict the use of nonabsorbable antibiotics to patients in whom small-intestine bacterial overgrowth has been confirmed, or to single-treatment cycles in patients who have IBS without constipation and who have not had a response to currently available symptom-directed therapies"

It may be a good idea to express wishes for more research. It is another thing to promote a email campaign to try influence the decision on the approval of a drug. The later is rather misguided - IMHO.

Cheers

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STABLE: ♂, IBS-D 50+ years - Science of IBS

The FODMAP Approach to Managing IBS Symptoms
Evidence-based Dietary Management of Functional GI Symptoms: The FODMAP Approach
FODMAP Chart & Cheatsheet
The Role of Food & Dietary Intervention in IBS

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