It is early days but there indications that researchers are getting a better idea of where and what to look for. There is a hint of a practical side. A previous study reported that clinical tests of a new generation of antihistamine drug, Ketotifin, that works on mast cells in the gut showed "decreases visceral hypersensitivity and improves intestinal symptoms in patients with irritable bowel syndrome". So the research in the new article appears to follow this general line of investigation in detail. It goes a bit further and shows that the effects of histamine, serotonin and proteases (enzymes that breakdown proteins) found in the extract of IBS suffers that excited gut nerves can be turned on and off using special chemicals.
It will be interesting to see where it leads them.
-------------------- STABLE: ♂, IBS-D 50+ years - Science of IBS
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Re: Inflammation identified in ibs
