Quote:

---

Because aloe is well-known as a gentle external treatment for minor burns and skin irritations, it's easy to assume that it would be safe for use internally as well. This is not necessarily true. Even though aloe vera is a plant, and thus "natural", it is still classified by the FDA as a Class 1 harsh stimulant laxative. There are substances called anthroquinones and anthrones in aloe, which produce a laxative effect by increasing colonic peristalsis and intestinal water content, by opening chloride channels of the colonic membrane to cause a net reduction of liquid absorption by the colon.

In plain English, this means that aloe causes faster and stronger contractions of the colon - something that people with IBS are already overly prone to, and which can cause violent abdominal cramps, painful spasms, and diarrhea.

The safety of aloe is another concern. All anthranoid laxatives (not just aloe, but senna and cascara sagrada as well) can cause melanosis coli, cathartic colon, and possibly increase the risk of colonic cancer. (In fact, genotoxicity studies show that aloe-containing laxatives pose cancer risks to humans even when used as directed.)
As if this isn't bad enough, chronic use of aloe can also lead to serious medical consequences such as fluid and electrolyte imbalance, steatorrhea, gastroenteropathy, osteomalacia, and vitamin and mineral deficiencies. When aloe is discontinued, radiographic and functional changes in the colon may only partially return to normal because of permanent drug-induced neuromuscular damage to the colon.

---