So sorry to hear about what has been going on, especially since you seemed to have gotten everything under control for so long.
I am not going to be too much help, since I am new to controlling this condition, but I have been suffering for 15+ years while getting 3 degrees (bs, ms, phd), so I know the stress (IBS-D while doing 4 years of work in the woods = fun). What I did recently (no one believed me before recently) was make sure to rule out all other conditions- had the colonoscopy and all the other tests. Then, my doctor gave me 2 really good meds to help get me though- the first is Welchol (cholesterol drug taken 1x daily to dry you out a bit- broad control of D without going into constipation for days- I had no side effects) and the other is Hyoscyamine sulfate (dissolves under tongue every 6 hrs as needed, very inexpensive ($4/mo), calms gut and stops D for a good bit without the 3 day constipation of Amod, although sometimes a 1-2 day lighter constipation).
I don't feel these are long term fixes, but when you are unable to take the time to take care of your self as I was when finishing up my doctoral work, you sometimes need a good short-term solution. Now, even though I am just as busy, I am working to get my stress under control, exercise again, and eat this new diet I just found.
Good luck to you!
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IBS-D with stress related bouts of C, 10+? years.
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