I have used it for seven month now. I highly recommend it to anyone. I am a D. I used to be my gastros worst case and the Align is what finally got me stable. Did you read the study on it? I have had one flare up since starting it and it lasted like two hours. In the old days I would have a attack not a flare up and the attack would last almost a week. My Dad was in ICU is when I had the flare up. Really stressed but only one flare up. Lisa