Irritable Bowel Syndrome Message Boards | Re: Seeking Advice ... Nexium and Immodium

Nexium should be taken 60 - 90 minutes before a meal since it reaches peak blood levels in 90 minutes. What is interesting it that the half life of the drug is also about 90 minutes which basically means that after taking one pill, after approximately four hours you have no more drug in you. If you find that you have worse acid reflux in the morning, then you should take it before breakfest. If your problems occur later in the day, adjust the time when you take it accordingly. The main point is that it needs to be taken on am empty stomach. If you take it with food you end up decreasing the amount of the available drug by 45-50% which is a huge drop.

Since the immodium question has already been answered the only part I will say is they can both be taken together.

As far as the other drugs you mentioned are concerned, you can take then with Nexium no problem. Just figure out when the best time for you to take Nexium is. The only drugs that have clinical data to suggest interactions with Nexium are penicillin and its relatives but a Dr. should have told you about possible side effects.

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