I have been doubling up every other day or so on Miralax, but I try to spread it out, because I always run out then so fast and my insurance will only cover it like every 25 days or so. In the morning I'll take my miralax about 30-45 minutes before I eat and it usually works. Then, alot of times I'll take it again on an empty tummy before dinner, like I did yesterday, and it didn't do anything! I did go good this morning, but I KNOW the zelnorm did not contribute. I'm going to not take it over the weekend and try it again maybe on monday and see what happens. I'm traveling also Tuesday-Friday, so that worries me! How soon do you go through a bottle of miralax? Are you taking any fiber supplements too? I cannot remember. Thanks!!!