I've used Imodium for a couple of years as "preventative maintenance" - with my doctor's blessing. Like Mags said, the after-effects are different for everyone. For me, it is slightly constipating - but nothing abnormal. And it's well worth it, to be able to do what I need to do! BTW, there've been some posts about Imodium-Advanced - apparently it contains sorbitol - I think that's the pesky ingredient? If you took that form, maybe that's bothering you. Seems like we have to read labels like they're contracts! Just a thought ....