Re: IBS and diabetes, this is important
02/24/05 06:57 PM
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AllisonL
Reged: 01/19/05
Posts: 54
Loc: Chapel Hill, North Carolina
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I am sorry, but there is no physiology to suggest that eating carbs causes the pancreas to "wear out" earlier, in either type 1 or type 2.
Limiting carbs might help ONLY if the person has some degree of obesity, and thus limiting carbs might limit caloric intake, and help promote wt loss, which might decrease insulin resistance. However, as far as carbohydrates provoking "glucose-toxicity" and pancreatic beta cell "burn-out" (or whatever you want to call it), I think there is little evidence that in the non-diabetic state that carbohydrate intake is detrimental.
Efforts to identify individuals at high risk for developing type I diabetes have thus far, proven disappointing, in terms of altering the progression to insulitis and autoimmune pancreatic beta cell destruction. Intensive diet, insulin treatment (before the onset of diabetes), and I think, even immunosuppressants, have not influenced the progression of this process, once various immunologic markers appear.
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