Hi David, I do take anti-spasmodic. Levisn/Hyoscyamnine. I could not make it day to day without it. Some people won; take it because ithas an after effect of drowsiness. I just take it and roll with the flow. everything I eat gives me gas, so wtihout it, I would have a poor quality of life. I love the stuff, hope ithelps you! They make itin a timed release caplet.