I don't know. This one is on my ankle and it started out as two smaller bites. I had jeans and socks on so I think a spider may have crawled up far enough to bite me on my ankle when I was standing in the overgrown flower bed adjusting the soaker hose. It gives me the willies to think about something crawling up my pants leg and biting me!
I went to Walmart on my lunch and got some Maximum Strength Lanacane that is suppose to numb and stop the itch on contact. I put some on and it's barely doing anything! They were out of Benedryl. Guess I'll have to try something else after work! The Lanacane said it would last for hours and only to apply 1-3 times a day! Right after I applied it, the itching moved to my foot and when I'd scratch my foot it was like there wasn't an itch there. Ya know what I mean. It's only been about 20 minutes since I applied the cream and the bite is itching just as bad as before I applied the cream!!