Irritable Bowel Syndrome Message Boards | Re: Anti-Inflammatory Diet?

The inflammation seen in some IBSers is a componet of the brain gut axis dysfuntion, even the immune system is connected to the brain as I was pointing out on the other thread, however there are dysfuntions in IBS that are not inflammation.

It can take an electron miscroscope to see some of it and some of it is embedded in the walls of the colon.

Here is a picture of two extremely important cells in IBS and how close they are to each other.

enterochromaffin cell or EC cell which stores and releases serotonin in the gut and the mast cell.

http://www.webpotential.com/falcon/uploadibspics3/images/gutreceptors.gif

MikeCA1870

Have you seen this?

In some people with IBS a subtle inflammation persists for some time after recovery from an initial infection and obvious inflammation. This can cause increased sensation in the intestines and changes in gut motility consistent with symptoms of IBS.

Video Corner: Inflammation

Inflammation
Does inflammation have a role in generating IBS symptoms? An interview with Gary M. Mawe, PhD, Professor of Anatomy and Neurobiology, University of Vermont, Burlington, VT. Dr. Mawe is a basic scientist.

http://www.aboutibs.org/site/learning-center/video-corner/inflammation

Increasingly our understanding of IBS is that it is a heterogeneous disorder � that is, multiple factors contribute to the well defined symptoms of the disorder. One of these suspected underlying dysfunctions involves serotonin, which is a neurotransmitter or messenger to nerves. Most serotonin in the body is in cells that line the gut where it senses what is going on and through receptors signals nerves that stimulate a response. The serotonin must then be reabsorbed (a process called re-uptake) into cells. This process appears to be disrupted in people with IBS.

Video Corner: Serotonin

http://www.aboutibs.org/site/learning-center/video-corner/serotonin

are you concern about your IBS diagnoses?

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My website on IBS is www.ibshealth.com

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