I've been using amitriptyline for almost a year now for pain management (from IBS and lupus). I am mostly IBS-D, although I do get C at times. I also started at 5 mg each night, for about a month or two, and then went up to 10 mg. It's really helped, in combination with Heather's diet, and with very few side effects (just feeling slightly groggy when I wake up in the morning). I haven't experienced serious constipation, but I have noticed things slow down. I still have a bm everyday, but it's normal now - not D. I am also able to incorporate a bit more IF, so this should help with any constipation you may experience.
Please know that such a low dose of amitriptyline will not affect your mood or cause weight gain; according to my doctors, you would need to take at least 10 times the amount I currently take to experience weight gain or mood changes.
Good luck with this medication!
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