It depends. I took a digestive enzyme and it was the worst thing I ever did. I had cramping so bad I was up all night one evening with cramping and I was vomiting like I had the flu but nothing was coming out. I was on them for about 3 weeks and finally realized that was causing the problem. I quit them and after a few days the cramping disappeared.
Everyone is different and alot of people on this website swear by them. So it is up to your discretion if you want to try them.