HI Beth! I wanted to post you because we seem to have similar stories. After I had my gallbladder out, I tried Miralax again since it worked well before surgery. Well, no such luck. I had terrible cramping, even on the smallest of doses. So I quit it, but now am super C again all of the time. Surgery def. didn't help that symptom AT ALL. So, I saw a new GI doc who told me to have a go wiht miralax again since it worked before. I mgiht have tried it too soon after surgery when my belly was really messed up. So, as of today I will take my first dose again and pray it works. It was my wonder drug for awhile, so I will keep you posted! How is the gallbladder symptoms treating you? I'm glad I had surgery, but really frustrated that I do indeed have IBS as well. At least the pains and such will never ocme back! Hope all is well:)