Comprehensive video from stanford univ. on ibs causes
#359787 - 07/19/10 05:23 AM
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This video presents the latest thoughts on this subject:
http://www.researchchannel.org/prog/displayevent.aspx?rID=26275&fID=1698
You'll need to select either windows media player or quicktime.
This video is one in http://healthlibrary.stanford.edu which includes videos on many health topics.
Cheers.
-------------------- ibs-d (pseudo)with pain and bloating
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This is the best description of what IBS is and its possible causes that I have seen.
One of the interesting things it explains is that when you consider the whole IBS population - including those that don't seek medical attention - the amount of psychiatric disorders (anxiety, depression, etc) is not any higher than in the normal population. It is clearly explained that IBS is not a psychological disorder. Also, the presenter puts an interesting prespective on short chain carbohydrates such as fructose, lactose & sorbitol and the role of fiber in managing IBS into clearer prespective.
Thank you for posting the link to this video.
-------------------- STABLE: ♂, IBS-D 50+ years - Science of IBS
The FODMAP Approach to Managing IBS Symptoms
Evidence-based Dietary Management of Functional GI Symptoms: The FODMAP Approach
FODMAP Chart & Cheatsheet
The Role of Food & Dietary Intervention in IBS
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Thanks for posting this video.
-------------------- My website on IBS is www.ibshealth.com
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This is an excellent presentation.
-------------------- My website on IBS is www.ibshealth.com
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Here's another article about this I found interesting: US News World Rep. 2000 Apr 3;128(13):50-1.
The wisdom of the gut. Those butterflies in your stomach are not just in your mind.
They refer to the gut as the second brain and defines IBS as being a malfunctioning of the big brain or little brain, or both, or someplace in between. It also talks about some meds that may be helpful. Im sure they have been mentioned on these boards I will have to look them up: Lotronex, Imitrex, Clonidine..
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I also found this a darn good overview. Anyone who doesn't have the gist of the brain/gut aspect (or doubts it) but wants to get it, can do so painlessly by watching. But my favorite thing about the discussion on the video is that it makes sense of and adds clarity to one of the most confusing parts of the discussion on this board (and elsewhere)! That is: There is no doubt that what works wonders for some of the IBS population overtly increases symptoms for others! kem (daughter w/ibs-d)
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They have know for many years now both the brain and the gut brain generate the symptoms. A dysregulation in the communication between the two. This is very important for IBSers to understand.
-------------------- My website on IBS is www.ibshealth.com
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Is brain gut interaction a theory or an established fact? I have read that it is not known whether the dysfunction is in the brain, the gut or in the interaction.
Also, he seems to be saying that the "vicious cycle" can start at any point (stress, infection, sibo, nerve damage, other causes (?)) and once started, the cycle will complete, i.e. all other symptoms will come about. Is this a correct interpretation?
Cheers.
-------------------- ibs-d (pseudo)with pain and bloating
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It is still a theory with fairly good clinical evidence to support it. It likely there are a number of IBS subtypes some of which the dysfunction will be in the gut, others in the brain and still others in the interaction between the two. It is early days in the research into this theory.
-------------------- STABLE: ♂, IBS-D 50+ years - Science of IBS
The FODMAP Approach to Managing IBS Symptoms
Evidence-based Dietary Management of Functional GI Symptoms: The FODMAP Approach
FODMAP Chart & Cheatsheet
The Role of Food & Dietary Intervention in IBS
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Actually the "brain gut interaction" is an established fact, just by functioning alone. In IBS both are operational to cause the symptoms. All pain is processed in the brain for one and stress can effect gut functioning in all people, but especially IBS.
What is not toally established is where the biomarkers are, like structural changes, in the gut brain or the brain or even the spinal cord.
The infection part really had to do with post infectious IBS where a person enteric infection, like dysentary and that goes away and a person gets PI IBS.
Sibo is a different condition, but some IBSers have that and IBS. Sibo is also a consequence and other problems can cause sibo that have nothing to do with IBS.
Part of that on bacteria was not totally sibo either, some was some of it wasn't, some of it was just about bacteria in the gut.
The presentation was from 2008, but they have known for many years IBS is a brain gut axis disorder, but its figuring out where all the problems are, like serotonin regulation, mast cells, the HPA axis, spinal cord and a lot more.
This is new from 2010. ULCA got a big grant to study the brain aspects and UNC the gut aspects. Then they are collaborating.
Irritable bowel syndrome associated with brain changes
Irritable bowel syndrome has been a tough disorder to understand. Studies have failed to show any structural problems in the gut that would account for the symptoms of pain, bloating, diarrhea and constipation. However, the disorder is real, affecting as many as 15% of Americans.
A new study has found a possible connection between IBS and the brain. Researchers at McGill University and UCLA used MRI scans to reveal changes in the brains of women with the disorder. The researchers took MRI scans of 55 IBS patients and 48 healthy women for comparison. The women with IBS tended to have different amounts of brain gray matter in certain areas; for example, decreases in gray matter in parts of the brain that govern attention and areas that suppress pain.
A link between the brain and chronic pain has been identified in other disorders, such as lower back pain, migraines, fibromyalgia and hip pain. The study on IBS suggests that, like these other conditions, the problem may be due to the brain's inability to inhibit the pain response.
"Discovering structural changes in the brain, whether they are primary or secondary to the gastrointestinal symptoms, demonstrates an 'organic' component to IBS and supports the concept of a brain-gut disorder," Emeran Mayer, a co-author of the study at UCLA, said in a news release. "Also, the findings remove the idea once and for all that IBS symptoms are not real and are 'only psychological.' The findings will give us more insight into better understanding IBS." By Shari Roan, Los Angeles Times
http://www.latimes.com/news/health/boostershots/la-heb-bowel-20100722,0,2369726.story
also just fyi, but a scientific theory is differnt then most people think when they think theory. Its not a hypothesis, but based on fact. Whereas a hypothesis is a stage to a scientific theory. But a a scientific theory is based on observable facts that have been tested and peer reviewed.
-------------------- My website on IBS is www.ibshealth.com
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