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Re: "Leaky Gut" and Glutathione new
      #352998 - 12/04/09 08:45 AM
Syl

Reged: 03/13/05
Posts: 5499
Loc: SK, CANADA

I presume you mean a breath test for SIBO. It depends on what they uses as the source of carbohydrate for the SIBO test. The standard SIBO test used lactulose and looked for an early rise in hydrogen levels in the breath test. They now know that an early rise in hydrogen after ingestion of lactulose is a normal response even individuals without SIBO. In an open on-line discussion with IBS experts from UNC I asked Dr. Drossman - a member of the Rome Foundation that designed the Rome III criteria used to diagnosis IBS - what was the best test for SIBO. He said that the hydrogen breath test using glucose as the carbohydrate source was the best. Again he re-iterated that the relationship between SIBO and IBS is tenuous at best.

If you decide to have a SIBO test please tell us how it goes.

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STABLE: ♂, IBS-D 50+ years - Science of IBS

The FODMAP Approach to Managing IBS Symptoms
Evidence-based Dietary Management of Functional GI Symptoms: The FODMAP Approach
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Some time soon I will post an overview of the research on melatonin and IBS. new
      #352999 - 12/04/09 09:39 AM
jhuggs

Reged: 03/18/09
Posts: 88
Loc: Erie, PA

Syl - as usual I'm interested in hearing what you have to say about this....I await patiently

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IBS-D & bloating.

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Re: "Leaky Gut" and Glutathione new
      #353000 - 12/04/09 09:55 AM
PMartin

Reged: 08/05/08
Posts: 140
Loc: Niagara Region

Thanks for the info and I'll certainly let you know how it turns out. I have to go to my GP for a referral (and put up with his reluctance like I'm bothering him) and then who knows how long it will take from there

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IBS-D. Or so a doctor says.

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Soon new
      #353002 - 12/04/09 11:05 AM
Syl

Reged: 03/13/05
Posts: 5499
Loc: SK, CANADA

Even thought I am retired currently I am a bit busy doing some international contract work. It should slow down in the next few days. When it does I will prepare the overview on melatonin.

Say - are you still taking a probiotic?

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STABLE: ♂, IBS-D 50+ years - Science of IBS

The FODMAP Approach to Managing IBS Symptoms
Evidence-based Dietary Management of Functional GI Symptoms: The FODMAP Approach
FODMAP Chart & Cheatsheet
The Role of Food & Dietary Intervention in IBS

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Re: Soon new
      #353003 - 12/04/09 12:02 PM
jhuggs

Reged: 03/18/09
Posts: 88
Loc: Erie, PA

I stopped taking it about 6 months ago and haven't noticed a difference...how about you?

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IBS-D & bloating.

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Re: Soon new
      #353004 - 12/04/09 12:29 PM
Syl

Reged: 03/13/05
Posts: 5499
Loc: SK, CANADA

I quite taking in summer because I always have less problems in the summer time. I have not restarted.

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STABLE: ♂, IBS-D 50+ years - Science of IBS

The FODMAP Approach to Managing IBS Symptoms
Evidence-based Dietary Management of Functional GI Symptoms: The FODMAP Approach
FODMAP Chart & Cheatsheet
The Role of Food & Dietary Intervention in IBS

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Vitamin D and Melatonin new
      #353011 - 12/04/09 05:20 PM
Windchimes

Reged: 09/05/09
Posts: 581
Loc: Northern California

Syl,

I have to wonder what the correlation between Vitamin D deficiency during winter months and the bodily melantonin supply is?

I garden and/or are outdoors a lot during the sunshine months of spring, summer, and into fall. However once winter sets in here, I have Seasonal Adjustment Disorder (SAD), and I find taking an extra Vitamin D supplement can help offset this somewhat.

Even so, I'm going back on the Melatonin, as this really DID help me sleep better at night, given the winter days are so short and there are more hours of darkness here than light. I sometimes tend to nap some during the day which doesn't help anything during the dark winter days. I do this as if I were a baby with my days and nights totally mixed up. I would prefer to get better zzz's at night and stay awake during the day.



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Senior female, IBS-D, presently stable thanks to Heather & Staff

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Re: Vitamin D and Melatonin new
      #353017 - 12/05/09 05:41 AM
Syl

Reged: 03/13/05
Posts: 5499
Loc: SK, CANADA

Vitamin D is produced by the skin in sunlight. The melatonin that affects sleep is produced in the pineal gland during the dark. Both of these are known to affect SAD.

However, melatonin that affects GI motility and sensitivity is produced by cells in the GI track. These cells produce 10 to 100 times as much melatonin than is found in the blood from the pineal gland. This melatonin does not contribute to sleep because it works locally and does not enter the blood stream. A recent study found that IBSers with sleep disorders that took 3 mg of melatonin at bed time had relief from pain and urgency but it had no affect on sleep. Perhaps the quality of sleep was better because the GI symptoms during sleep were better.

I am going to write a long post on melatonin and IBS in a few days.

Thanks for your note.

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STABLE: ♂, IBS-D 50+ years - Science of IBS

The FODMAP Approach to Managing IBS Symptoms
Evidence-based Dietary Management of Functional GI Symptoms: The FODMAP Approach
FODMAP Chart & Cheatsheet
The Role of Food & Dietary Intervention in IBS

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Re: Vitamin D and Melatonin new
      #353019 - 12/05/09 06:44 AM
Windchimes

Reged: 09/05/09
Posts: 581
Loc: Northern California

Good morning Syl!

What you wrote here makes perfect sense to me, and I am looking forward to your further expansion on melatonin. Hopefully you will make that a new post so that this one doesn't get too long...

In any case, and speaking from personal experience, when I have taken 3 mg of melatonin in the past, I WAS drowsy within 30 minutes. If I attempted to stay up longer working on my computer, I kept 'nodding off' sitting up. For me, it was definitely a sleeping aid and no doubt also helped control my gastrointestinal contractions during the night as well (unknown to me). At that time I had not been experiencing any present GI symptoms, just needed to sleep more soundly. Even so, it could have been GI contractions unknown to me that was causing my inability to fall asleep easily in the first place.

The bottom line... with 3 mg of melatonin I fell asleep in 30 minutes and slept extremely well for at least 6 hours.

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Senior female, IBS-D, presently stable thanks to Heather & Staff

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Re: Vitamin D and Melatonin new
      #353030 - 12/05/09 11:42 AM
Gerikat

Reged: 06/21/09
Posts: 1285


Yes, Windchimes, melatonin works for me also, but not for any IBS symptoms. I have to take 4 mg and I have to take it at least 1 to 1 1/2 hours before bed.

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