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Splenda is the trade name for sucralose. I.e., sucralose and Splenda are the same thing.
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I avoid splenda as well as other artificial sweeteners that are not supposed to be absorbed by our bodies. That's why they have no calories - they don't get absorbed. Now think about psyllim husk which also doesn't get absorbed - anyone noticed more bloating after trying Metamucil? I sure did.
Sometimes I use aspartame and seem to be doing OK with that.
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IBS-C, bloating, cramps
pregnant 
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I haven't noticed any ill effects from saccharine or aspartame---only with Splenda. Of course, that doesn't Splenda is necessarily worse than the other sweeteners; itjust means my body is sensitive to it & not the others.
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I'm 99% sure I'm fine with aspartame too. Splenda, I'm not so sure...
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IBS-A since age 12, and fructose sensitive; with the exception of my pregnancy, have been following Heather's diet since Nov. 19, 2007.
Taking 12g of Acacia per day. Relatively stable since March 2008!
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