Help For Irritable Bowel Syndrome (IBS) - Education, Support, & Self Help for Irritable Bowel Syndrome
Heather & Company View Cart
Shop for IBSIBS Message BoardsIBS News & ReviewsStore Finder
Home
IBS Diet & Recipes
IBS Books
IBS Supplements
Yoga for IBS
Hypnosis for IBS
Tummy Teas
Get The IBS Diet Cheat Sheet
Get Trigger Foods, Safe Foods, Ten Commandments of Eating for IBS, More!

Enter First Name:

Enter Email:

We value your privacy


All Boards >> Irritable Bowel Syndrome Research Library

HeatherAdministrator

Reged: 12/09/02
Posts: 7423
Loc: Seattle, WA
Abdominal Bloating: Relation to Rectal Hypersensitivity and Menstrual Cycle
06/27/04 01:55 PM

Abdominal Bloating: Relation to Rectal Hypersensitivity and Menstrual Cycle

Lin Chang, MD

Abdominal bloating and visible abdominal distension are commonly reported by patients with IBS.[17] Despite the introduction of tegaserod, which has been shown to relieve symptoms of bloating in female patients with IBS-C,[18] bloating can still be challenging to treat because of the lack of understanding of the pathophysiologic mechanisms underlying these common symptoms.[19] While some patients with bloating have associated abdominal distension, others do not. Although patients with IBS with abdominal bloating, with and without associated visible abdominal distension, are quite similar in the majority of parameters, eg, those with both bloating and distension are more likely to be female, are more likely to report a greater perceived symptom severity, and are more likely to have less diurnal variation in symptoms.[20] In addition, abdominal bloating is reportedly worse in women during the late luteal and early menses phases of the menstrual cycle.[21]

Lea and colleagues[22] performed several studies to further evaluate the impact of these associated factors (ie, diurnal variation, abdominal distension, and menstrual cycle) in patients with IBS with bloating. In one study, they evaluated the diurnal variation of abdominal girth in 16 patients with IBS-C, 21 with IBS-D, and in 20 healthy control subjects. Abdominal distension was measured using a recently validated objective technique of Ambulatory Abdominal Inductance Plethysmography.[23] Abdominal girth was greatest in the early evening in approximately 60% of both IBS-C and IBS-D patients, but only correlated with worsening bloating symptoms in the IBS-C patients.

In a second study,[24] these investigators assessed whether rectal sensitivity differed between female patients with IBS with abdominal bloating, with and without increased abdominal distension (total n = 37). Those patients who did not exhibit physical abdominal distension (compared with healthy controls) had significantly lower rectal pain thresholds than both patients with IBS who were distended and healthy controls. The investigators concluded that the symptom of bloating in the absence of visible abdominal distension may be due to increased visceral sensitivity to gastrointestinal events.

In their third study, Lea and colleagues[25] sought to determine whether perimenstrual bloating is associated with abdominal distension. Abdominal girth was recorded for 24 hours in 12 women with IBS and in 10 healthy female volunteers during the various menstrual cycle phases. Both women with IBS and control females reported more bloating during menses and the premenstrual phase, although bloating was rated as more severe in the patients than in the controls. However, abdominal girth was not different between the different phases of the menstrual cycle in IBS patients or in controls. Taken in conjunction with the results from the first study and with the previous finding that rectal perception is increased during menses compared with the other menstrual cycle phases in women with IBS,[26] these results lend support to the hypothesis that abdominal bloating is related to visceral hypersensitivity in IBS.

Summary. Abdominal bloating is a common symptom reported by patients with IBS, although its pathophysiology is not well understood. Several findings suggest that abdominal bloating may be related to visceral hypersensitivity: (1) bloating without distension is associated with lowered rectal pain thresholds; (2) bloating is reported as worse in the premenstrual and early menses phases of the menstrual cycle; and (3) rectal sensitivity is increased during menses compared with the other phases in women with IBS. If abdominal bloating is related to visceral hypersensitivity, it is not clear whether this is due primarily to visceral hyperalgesia (ie, increased pain perception to noxious visceral events) or to a hypervigilance towards expected aversive events arising from the viscera.

http://www.medscape.com/viewarticle/480232

--------------------
Heather is the Administrator of the IBS Message Boards. Shes the author of Eating for IBS and The First Year: IBS, and the CEO of Heather's Tummy Care. Join her IBS Newsletter. Meet Heather on Facebook!

Post Extras Print Post Remind Me! Notify Moderator

Entire thread
Subject Posted by Posted on
* Gender / Hormones HeatherAdministrator 07/14/03 01:57 PM
. * Women, Hormones and IBS HeatherAdministrator 03/11/14 02:09 PM
. * Fennel is an effective herbal drug for menstrual pain HeatherAdministrator 08/27/13 11:29 AM
. * Constipation and Risk of Cardiovascular Disease among Postmenopausal Women HeatherAdministrator 08/03/11 03:58 PM
. * Differences in Gastrointestinal Symptoms According to Gender in Rome II Positive IBS and Dyspepsia HeatherAdministrator 03/11/10 01:51 PM
. * Gender-related differences in prepulse inhibition of startle in irritable bowel syndrome HeatherAdministrator 03/11/10 01:48 PM
. * No evidence of sex differences in heritability of irritable bowel syndrome HeatherAdministrator 03/31/08 11:36 AM
. * Acupuncture for the treatment of pain from a gender perspective. HeatherAdministrator 03/31/08 11:27 AM
. * The menstrual cycle and its effect on inflammatory bowel disease and irritable bowel syndrome HeatherAdministrator 11/07/07 02:35 PM
. * Irritable Bowel Syndrome Is More Common in Women Regardless of the Menstrual Phase HeatherAdministrator 11/07/07 02:31 PM
. * Pelvic floor dysfunction and IBS in patients with interstitial cystitis. HeatherAdministrator 10/10/07 12:33 PM
. * Women with IBS have abnormal pain modulation HeatherAdministrator 10/10/07 12:01 PM
. * Anxiety or Depression with IBS Affects More Women Than Men HeatherAdministrator 09/24/07 11:31 AM
. * Colonoscopies more difficult and painful for women and people with IBS HeatherAdministrator 09/24/07 11:22 AM
. * Role of gender and early childhood in constipation HeatherAdministrator 09/13/07 11:09 AM
. * Changes in Bowel Function: Pregnancy and the Puerperium HeatherAdministrator 03/01/07 01:39 PM
. * Drugs for gastrointestinal disorders in pregnant women. HeatherAdministrator 05/13/06 03:20 PM
. * Functional bowel disorders in patients with pelvic organ prolapse and incontinence HeatherAdministrator 12/08/05 12:10 PM
. * Sex specific alterations in autonomic function among patients with irritable bowel syndrome HeatherAdministrator 11/12/05 01:16 PM
. * Women With Interstitial Cystitis at Risk for Irritable Bowel Syndrome and Depression HeatherAdministrator 09/22/05 04:39 PM
. * Women and Men Perceive Pain Differently HeatherAdministrator 09/13/05 12:55 PM
. * Overlapping Conditions in Women With Irritable Bowel Syndrome HeatherAdministrator 04/24/05 03:58 PM
. * Bowel habit in irritable bowel syndrome in women: Defining an alternator HeatherAdministrator 04/10/05 06:18 PM
. * Recognition and treatment of irritable bowel syndrome among women with chronic pelvic pain HeatherAdministrator 03/28/05 12:18 PM
. * Irritable bowel syndrome, chronic pelvic inflammatory disease and endometriosis HeatherAdministrator 02/19/05 05:43 PM
. * A gene for diarrhoea-predominant IBS in women? HeatherAdministrator 11/28/04 02:21 PM
. * Autonomic Cardiovascular Responses Are Impaired in Women With Irritable Bowel Syndrome HeatherAdministrator 09/12/04 03:41 PM
. * Abdominal Bloating: Relation to Rectal Hypersensitivity and Menstrual Cycle HeatherAdministrator 06/27/04 01:55 PM
. * Catching Colon Cancer in Women Can Be Tough HeatherAdministrator 04/13/04 03:32 PM
. * Women More Sensitive to Pain Than Men HeatherAdministrator 04/13/04 03:31 PM
. * Gender Differences In Brain Response To IBS Pain HeatherAdministrator 11/18/03 03:32 PM
. * After Menopause, IBS Lessens in Women HeatherAdministrator 11/04/03 03:34 PM
. * Is hormone replacement therapy associated with an increased risk of irritable bowel syndrome? HeatherAdministrator 07/25/03 11:43 AM
. * Sleep disturbance influences gastrointestinal symptoms in women with irritable bowel syndrome. HeatherAdministrator 07/18/03 01:00 PM
. * Symptoms across the menstrual cycle in women with irritable bowel syndrome. HeatherAdministrator 07/18/03 12:58 PM
. * Does a physically active lifestyle improve symptoms in women with irritable bowel syndrome? HeatherAdministrator 07/18/03 12:54 PM
. * Relation between hysterectomy and the irritable bowel HeatherAdministrator 07/18/03 11:48 AM
. * Diagnosis and management of IBS, constipation, and diarrhea in pregnancy. HeatherAdministrator 07/18/03 11:47 AM
. * Physician perception of IBS management in women and men. HeatherAdministrator 07/15/03 06:38 PM
. * Gender issues in the management of IBD and IBS HeatherAdministrator 07/15/03 06:11 PM
. * Gender differences in gut transit HeatherAdministrator 07/15/03 06:07 PM
. * Bowel dysfunction in postmenopausal women. HeatherAdministrator 07/15/03 06:04 PM
. * Irritable Bowel Syndrome Worse During Periods HeatherAdministrator 07/14/03 03:25 PM
. * Sex-related differences in IBS patients: Central processing of visceral stimuli HeatherAdministrator 07/14/03 02:40 PM

Extra information
0 registered and 0 anonymous users are browsing this forum.

Moderator:  Heather 



Permissions
You cannot post until you login
You cannot reply until you login
HTML is enabled
UBBCode is enabled

Thread views: 103617

Jump to

| Privacy statement Help for IBS Home

*
UBB.threads™ 6.2

LEGAL DISCLAIMER - This website is not intended to replace the services of a physician, nor does it constitute a doctor-patient relationship. Information on this web site is provided for informational purposes only and is not a substitute for professional medical advice. You should not use the information on this web site for diagnosing or treating a medical or health condition. If you have or suspect you have an urgent medical problem, promptly contact your professional healthcare provider.

Any application of the recommendations in this website is at the reader's discretion. Heather Van Vorous, HelpForIBS.com, and Heather & Company for IBS, LLC are not liable for any direct or indirect claim, loss or damage resulting from use of this website and/or any web site(s) linked to/from it. Readers should consult their own physicians concerning the recommendations on these message boards.



Home | Shop for IBS | IBS Message Boards | IBS News & Reviews | IBS Support Groups
IBS Diet & Recipes | IBS Books | IBS Supplements | Yoga for IBS | Hypnosis for IBS
IBS Tummy Teas� | Irritable Bowel Syndrome Glossary

About Us | IBS Links | Search this Site | Site Map | Shipping & Returns | Privacy & Security
Contact Us | For Doctors & Dietitians | Wholesale | Co-packing Services

� 1999-2009, Heather Van Vorous, HelpForIBS.com, Heather & Company for IBS, LLC.
All information & art is proprietary and may not be duplicated.
All rights reserved.

Legal & Medical Disclaimer

Website Design