Help For Irritable Bowel Syndrome (IBS) - Education, Support, & Self Help for Irritable Bowel Syndrome
Heather & Company View Cart
Shop for IBSIBS Message BoardsIBS News & ReviewsStore Finder
Home
IBS Diet & Recipes
IBS Books
IBS Supplements
Yoga for IBS
Hypnosis for IBS
Tummy Teas
Get The IBS Diet Cheat Sheet
Get Trigger Foods, Safe Foods, Ten Commandments of Eating for IBS, More!

Enter First Name:

Enter Email:

We value your privacy


All Boards >> Irritable Bowel Syndrome Research Library

HeatherAdministrator

Reged: 12/09/02
Posts: 7677
Loc: Seattle, WA
Takeda, Enterome to collaborate on microbiome-based drugs for IBD, IBS, other GI disorders
      01/11/16 03:21 PM

Takeda, Enterome to collaborate on microbiome-based drugs for IBD, IBS, other GI disorders
January 6, 2016

Takeda Pharmaceuticals and Enterome Bioscience SA today announced they will collaborate on research and development of new potential therapies aimed at microbiome targets believed to be involved in GI disorders like inflammatory bowel disease and irritable bowel syndrome, according to a press release.

“This strategic collaboration with Takeda is a significant achievement for Enterome and represents an important step towards realizing the full potential of our expertise and unique capabilities in unlocking the microbiome to generate new therapeutic solutions to serious diseases,” Pierre Belichard, CEO of Enterome, said in the press release. “We are delighted to begin this new collaboration, which will combine our continuing leadership in the microbiome space and Takeda’s global therapeutic drug discovery and development capabilities. It is also an important step for Enterome towards achieving its ambition to become a leading global biopharmaceutical company in the microbiome space.”

The collaboration agreement entails Enterome will support discovery of potential novel small molecules or biologics derived from gut microbiota using its proprietary metagenomics platform, and the GI targets to which these agents will be directed will be selected by both companies. Takeda will have exclusive, global license options on selected agents and will lead their regulatory and clinical development and commercialization efforts.

Moreover, Takeda will provide Enterome with 3-year research and development funding up front. For each molecule discovered, Enterome will be able to receive additional payments in the form of option exercise, development, regulatory and commercial milestone payments, and for any products Takeda commercializes, Enterome will be able to receive potential tiered royalties on net sales.

“At Takeda, innovation is at the core of our efforts to bring new therapies to patients in the future,” Gareth Hicks, PhD, head of gastroenterology drug discovery for Takeda, said in the press release. “In partnering with scientists at Enterome, who perform cutting-edge research into microbiome-derived agents, Takeda is able to explore this exciting science and bring innovative therapies forward.”

Disclosures: Belichard reports he is an employee of Enterome, and Hicks reports he is an employee of Takeda.


http://www.healio.com/gastroenterology/therapeutics-diagnostics/news/online/%7B3e55bab3-4cbd-45f3-94f4-cb0e78c55645%7D/takeda-enterome-to-collaborate-on-microbiome-based-drugs-for-ibd-ibs-other-gi-disorders

--------------------
Heather is the Administrator of the IBS Message Boards. She’s the author of Eating for IBS and The First Year: IBS, and the CEO of Heather's Tummy Care. Join her IBS Newsletter. Meet Heather on Facebook!

Post Extras Print Post   Remind Me!     Notify Moderator

Entire thread
Subject Posted by Posted on
* General IBS / Bowel Dysfunction HeatherAdministrator 07/14/03 01:56 PM
. * April is IBS Awareness Month: 10 recent advances in research, diagnostics HeatherAdministrator   04/16/18 02:05 PM
. * Bacteria can trigger stomach cancer HeatherAdministrator   08/25/17 04:11 PM
. * Fecal microbiota transplantation improved symptoms and quality of life in patients with IBS HeatherAdministrator   05/09/17 01:28 PM
. * Autism symptoms improve after fecal transplant, small study finds HeatherAdministrator   01/26/17 02:54 PM
. * Microbiota and arthritis: correlations or cause? HeatherAdministrator   02/19/16 01:09 PM
. * Takeda, Enterome to collaborate on microbiome-based drugs for IBD, IBS, other GI disorders HeatherAdministrator   01/11/16 03:21 PM
. * Risk factors for IBS in military include stress, infectious gastroenteritis HeatherAdministrator   01/11/16 03:19 PM
. * Risk Factors ID'd for Fecal Transplant Failure HeatherAdministrator   10/26/15 03:06 PM
. * Blood Test Helps Some IBS Patients Get Firm Diagnosis HeatherAdministrator   10/15/15 10:51 AM
. * Differences in IBS patients' microbiota more significant in feces vs. mucosa HeatherAdministrator   09/28/15 02:14 PM
. * Higher reported cat dander sensitization rate may explain asthma prevalence in IBS patients HeatherAdministrator   09/14/15 03:32 PM
. * Picky Eaters Have Extra Helpings of Anxiety, Depression HeatherAdministrator   08/05/15 03:42 PM
. * Prediabetes Patients Have Fewer Gut Bugs HeatherAdministrator   03/09/15 03:08 PM
. * FDA approves Eclipse System for fecal incontinence in women HeatherAdministrator   02/23/15 01:35 PM
. * Fecal transplant leads to sudden obesity HeatherAdministrator   02/23/15 01:24 PM
. * New Criteria Would Double Fibromyalgia Cases HeatherAdministrator   02/10/15 04:17 PM
. * 2014 FDA approvals in gastroenterology HeatherAdministrator   01/12/15 03:36 PM
. * Colonoscopy prep affects gut bacteria HeatherAdministrator   01/07/15 03:58 PM
. * The Bile-IBS Link HeatherAdministrator   12/15/14 03:18 PM
. * Ineffective Pain Meds in IBS Patients Related to Immune System Changes HeatherAdministrator   12/09/14 11:34 AM
. * Volatile organic compounds accurate biomarkers for IBS in children HeatherAdministrator   10/27/14 01:59 PM
. * Researchers develop, validate eight GI symptom scales HeatherAdministrator   10/07/14 02:17 PM
. * Sleep Measures Can Help Predict Next-Day Symptoms in IBS Female Patients HeatherAdministrator   09/17/14 02:27 PM
. * Domestic violence may trigger irritable bowel syndrome HeatherAdministrator   09/17/14 02:15 PM
. * All IBS subtypes have similar symptom severity HeatherAdministrator   09/05/14 03:50 PM
. * Gut microbiome can diagnose colorectal cancer? HeatherAdministrator   08/12/14 11:21 AM
. * Sacral nerve stimulation does not help IBS HeatherAdministrator   07/15/14 02:57 PM
. * Small Study of IBS Patients Suggests Symptom Improvement with Fecal Microbiota Transplant HeatherAdministrator   06/27/14 04:15 PM
. * Vitamin D Role in Fecal Incontinence? HeatherAdministrator   05/22/14 05:03 PM
. * Colonic bile acid exposure influenced IBS symptoms HeatherAdministrator   05/22/14 04:50 PM
. * Good Vibration(s) for Constipation? HeatherAdministrator   05/12/14 03:55 PM
. * Can you give your spouse IBS? HeatherAdministrator   04/22/14 02:12 PM
. * Factors linked to chronic constipation HeatherAdministrator   04/07/14 02:06 PM
. * IBS patients' health perceptions focus on non-GI issues HeatherAdministrator   04/07/14 01:35 PM
. * Is IBS Funding a Joke? HeatherAdministrator   01/17/14 11:53 AM
. * Blood Test for IBS? HeatherAdministrator   10/16/13 01:30 PM
. * Gut microbes closely linked to proper immune function HeatherAdministrator   09/17/13 02:09 PM
. * More bugs in your gut = better health, lower body weight. HeatherAdministrator   08/30/13 11:32 AM
. * Top 10 Questions to Ask Your Doc about IBS HeatherAdministrator   08/16/13 01:01 PM
. * Had your gallbladder out? You may not have IBS. HeatherAdministrator   08/16/13 01:01 PM
. * IBS Quick Tip - Bloating Relief HeatherAdministrator   08/16/13 01:00 PM
. * Hot Summer Weather Affects IBS HeatherAdministrator   08/16/13 12:58 PM
. * Chronic Heartburn May Raise Odds for Throat Cancer HeatherAdministrator   05/29/13 09:57 AM
. * Support the Functional Gastrointestinal and Motility Disorders Research Enhancement Act HeatherAdministrator   04/22/13 01:52 PM
. * IBS increased risk for osteoporosis, related fractures HeatherAdministrator   03/18/13 01:23 PM
. * Weight Loss Better Than Drugs for Heartburn HeatherAdministrator   02/13/13 10:42 AM
. * Greater antibiotic use raises incidence of C. diff infections HeatherAdministrator   10/31/12 11:35 AM
. * No evidence supports colonic irrigation for IBS HeatherAdministrator   06/15/12 03:11 PM
. * Two Questions For Your Doctor Before A Colonoscopy HeatherAdministrator   06/15/12 03:06 PM
. * Dietary cleanses risky HeatherAdministrator   06/15/12 01:22 PM
. * Army of gut microbes keep us fit and healthy HeatherAdministrator   06/15/12 01:19 PM
. * Irritable Bowel Syndrome (IBS) and Bacteria in Gut HeatherAdministrator   05/30/12 11:59 AM
. * Can a Gut Check Boost Sleep, Sex and Brain Power? HeatherAdministrator   05/02/12 10:27 AM
. * April is IBS Awareness Month HeatherAdministrator   04/23/12 01:47 PM
. * Fecal matter, delivered by enema, helps heal in nine out of 10 cases HeatherAdministrator   04/23/12 01:34 PM
. * Too Many Americans Skipping Colon Cancer Screening HeatherAdministrator   03/13/12 05:02 PM
. * Chronic Heartburn a Growing Problem in U.S. HeatherAdministrator   01/05/12 01:46 PM
. * Fecal Transplants Show Promise for Gastrointestinal Ills HeatherAdministrator   11/23/11 02:37 PM
. * Stomach bug giardia linked to IBS and chronic fatigue syndrome HeatherAdministrator   10/06/11 07:02 PM
. * Gut analysis with smart pill could be new key to IBS treatment HeatherAdministrator   10/06/11 06:58 PM
. * Colon Cleansing Not Backed by Science and Can Be Dangerous HeatherAdministrator   08/03/11 03:45 PM
. * Gut Bacteria Falls Into Three Major Types HeatherAdministrator   05/05/11 11:13 AM
. * Stress May Alter Gut Bacteria and Hurt Immune System HeatherAdministrator   04/06/11 04:31 PM
. * Factors associated with co-morbid irritable bowel syndrome and chronic fatigue HeatherAdministrator   02/10/11 10:21 AM
. * Subtypes of Irritable Bowel Syndrome Based on Abdominal Pain/Discomfort Severity and Bowel Pattern HeatherAdministrator   02/10/11 10:14 AM
. * Irritable Bowel Syndrome Is Not In Your Head HeatherAdministrator   09/24/10 02:42 PM
. * Pain perception during colonoscopy higher in IBS patients than in non-IBS patients HeatherAdministrator   07/21/10 03:52 PM
. * Can Choir Singing Improve Irritable Bowel Syndrome? HeatherAdministrator   06/24/10 01:48 PM
. * Patients with IBS are NOT more likely to develop polyps, colon cancer HeatherAdministrator   05/12/10 01:18 PM
. * Rome Foundation Introduces Clinical Tool For Diagnosis Of Functional Gastrointestinal Disorders HeatherAdministrator   04/12/10 11:40 AM
. * Rotating Shift Workers At More Risk For Irritable Bowel Syndrome HeatherAdministrator   04/12/10 11:39 AM
. * Irritable bowel syndrome (IBS) does seem to run in families HeatherAdministrator   04/02/10 11:14 AM
. * IBS Does Not Increase Risk of Colon Cancer or IBD HeatherAdministrator   03/12/10 11:30 AM
. * Validation of Symptom-Based Diagnostic Criteria for Irritable Bowel Syndrome HeatherAdministrator   03/11/10 01:53 PM
. * Importance of early diagnosis in patients with irritable bowel syndrome HeatherAdministrator   03/11/10 01:44 PM
. * Altered profiles of intestinal microbiota and organic acids may be the origin of symptoms in irritable bowel syndrome HeatherAdministrator   03/11/10 01:12 PM
. * Constipation: a potential cause of pelvic floor damage? HeatherAdministrator   09/29/09 12:10 PM
. * Patients say they would give up 25% of their remaining life to be rid of IBS HeatherAdministrator   08/28/09 01:21 PM
. * IBS - it's the pain and the stigma HeatherAdministrator   08/28/09 01:16 PM
. * Wasington state retailers required to make bathrooms available to people with IBS and IBD HeatherAdministrator   05/13/09 01:06 PM
. * Development of an educational intervention for patients with Irritable Bowel Syndrome HeatherAdministrator   02/06/09 12:20 PM
. * Prevalence of Functional Gastrointestinal Disorders in Patients With Fibromyalgia and the Role of Psychologic Distress HeatherAdministrator   01/22/09 04:47 PM
. * Highlights of ACG's New Recommendations on IBS Therapies HeatherAdministrator   01/09/09 11:10 AM
. * Irritable Bowel Syndrome Can Have Genetic Causes HeatherAdministrator   12/16/08 11:42 AM
. * Is IBS part of a cascade of events? HeatherAdministrator   10/27/08 10:56 AM
. * Contributions of Pain Sensitivity and Colonic Motility to IBS Symptom Severity HeatherAdministrator   10/21/08 02:38 PM
. * Subgroup classification in irritable bowel syndrome patients over time HeatherAdministrator   10/09/08 01:56 PM
. * Genetic factors may play a role in IBS HeatherAdministrator   09/26/08 02:52 PM
. * Genetics of Irritable Bowel Syndrome HeatherAdministrator   08/27/08 12:43 PM
. * Irritable bowel syndrome: an international study of symptoms in eight countries HeatherAdministrator   08/07/08 12:42 PM
. * Gallstones, cholecystectomy and irritable bowel syndrome HeatherAdministrator   04/22/08 04:01 PM
. * Abdominal Bloating in Employed Adults: Prevalence, Risk Factors, and Association With Other Bowel Disorders HeatherAdministrator   04/22/08 02:07 PM
. * IBS is keeping me hostage! HeatherAdministrator   03/14/08 11:12 AM
. * Abdominal Bloating and Distension in Functional Gastrointestinal Disorders HeatherAdministrator   02/28/08 03:16 PM
. * Psychological distress and GI symptoms are related to severity of bloating HeatherAdministrator   02/28/08 02:40 PM
. * Irritable Bowel Syndrome's Possible Genetic Link HeatherAdministrator   02/04/08 10:43 AM
. * Patients with allergies appear to have a higher incidence of irritable bowel syndrome (IBS) HeatherAdministrator   02/04/08 10:19 AM
. * Train operator suffering from irritable bowel syndrome sues for lost wages HeatherAdministrator   12/06/07 02:45 PM
. * IBS may not affect small bowel transit time, but age does HeatherAdministrator   10/24/07 01:56 PM
. * Diagnostic work-up of IBS HeatherAdministrator   10/24/07 12:15 PM
. * Neural mechanisms of pelvic organ cross-sensitization. HeatherAdministrator   10/10/07 11:41 AM
. * Incidence and Prognosis of Post-Infectious Irritable Bowel Syndrome HeatherAdministrator   09/13/07 11:21 AM
. * Irritable bowel syndrome and the Rome III criteria: for better or for worse? HeatherAdministrator   08/28/07 04:15 PM
. * Quality of Life in Patients With IBD and IBS Differs Between Subjects Recruited from Clinic or the Internet HeatherAdministrator   08/09/07 11:31 AM
. * Fecal microbiota of irritable bowel syndrome patients differs significantly from that of healthy subjects HeatherAdministrator   08/02/07 03:08 PM
. * Irritable bowel syndrome and bloating HeatherAdministrator   08/02/07 03:02 PM
. * IBS And Restless Legs Syndrome Linked HeatherAdministrator   08/02/07 02:50 PM
. * Overlapping upper and lower gastrointestinal symptoms in irritable bowel syndrome patients HeatherAdministrator   06/20/07 01:49 PM
. * Bacterial Overgrowth Apparently NOT Important in IBS HeatherAdministrator   06/06/07 10:51 AM
. * Irritable bowel syndrome: patients' attitudes, concerns and level of knowledge HeatherAdministrator   05/23/07 02:32 PM
. * Influence of genetics on irritable bowel syndrome HeatherAdministrator   05/23/07 02:25 PM
. * Diarrhea-predominant irritable bowel syndrome and possible microscopic colitis HeatherAdministrator   05/11/07 03:37 PM
. * Breath Methane Levels Correlate With Constipation in IBS HeatherAdministrator   04/28/07 10:13 AM
. * 7 common myths – and facts – about IBS HeatherAdministrator   04/11/07 04:17 PM
. * Symptomatic overlap between irritable bowel syndrome and microscopic colitis HeatherAdministrator   03/18/07 04:48 PM
. * Reactions to a guided self-management intervention in a randomised controlled trial for IBS HeatherAdministrator   03/18/07 04:39 PM
. * Audit of Subtypes of Functional Constipation in a Gastroenterology Referral Center HeatherAdministrator   03/18/07 04:26 PM
. * New insights into the pathogenesis and pathophysiology of irritable bowel syndrome HeatherAdministrator   03/01/07 01:17 PM
. * Overly Anxious and Driven People Prone to Irritable Bowel Syndrome HeatherAdministrator   03/01/07 12:37 PM
. * Paid Participants Sought for Online IBS University Research Study HeatherAdministrator   02/26/07 11:43 AM
. * Physical activity and intestinal gas clearance in patients with bloating. HeatherAdministrator   02/04/07 04:11 PM
. * Familial Aggregation in Constipated Subjects HeatherAdministrator   01/21/07 04:12 PM
. * Participate in a research study looking at attitudes and opinions about people who have IBS HeatherAdministrator   12/29/06 04:15 PM
. * Most important barriers to the optimal management of patients with IBS-C and chronic constipation HeatherAdministrator   12/01/06 01:23 PM
. * Traveler's Diarrhea May Boost Risk of Irritable Bowel Syndrome HeatherAdministrator   10/14/06 02:28 PM
. * Irritable Bowel Syndrome Linked to Migraine, Fibromyalgia, and Depression HeatherAdministrator   10/14/06 02:24 PM
. * Restricted Fetal Growth Linked to Irritable Bowel Syndrome HeatherAdministrator   10/14/06 02:21 PM
. * The Science of IBS - Postinfectious IBS and Small Intestinal Bacterial Overgrowth HeatherAdministrator   09/30/06 03:23 PM
. * The Science of IBS - Environment and Genetics HeatherAdministrator   09/17/06 02:36 PM
. * Making a Positive Diagnosis of IBS HeatherAdministrator   08/19/06 11:56 AM
. * IBS -- Review and What's New - Abstract and Introduction HeatherAdministrator   08/05/06 03:58 PM
. * Treatment of Functional Diarrhea HeatherAdministrator   07/17/06 01:54 PM
. * Prevalence and Incidence of Chronic Constipation HeatherAdministrator   07/05/06 05:35 PM
. * Rome III Diagnostic Criteria HeatherAdministrator   06/12/06 04:16 PM
. * Determinants of Healthcare-Seeking Behaviour in IBS HeatherAdministrator   06/04/06 11:48 AM
. * Genetic cause for irritable bowel syndrome HeatherAdministrator   05/29/06 01:48 PM
. * Cytokines May Provide Marker for Irritable Bowel Syndrome HeatherAdministrator   05/14/06 05:04 PM
. * Introduction to IBS Constipation - the Problem HeatherAdministrator   05/14/06 04:57 PM
. * Gender, Age, Society, Culture, and the Patient's Perspective in IBS HeatherAdministrator   05/13/06 03:16 PM
. * What IBS Patients Need - But Don't Get - From Their Physicians HeatherAdministrator   05/08/06 04:37 PM
. * Antibiotic use and irritable bowel syndrome (IBS). HeatherAdministrator   04/15/06 04:02 PM
. * Older Versus Younger Patients with Irritable Bowel Syndrome HeatherAdministrator   04/15/06 03:11 PM
. * Prevalence of irritable bowel syndrome and depression in fibromyalgia HeatherAdministrator   04/15/06 03:04 PM
. * Intestinal serotonin signalling in irritable bowel syndrome HeatherAdministrator   04/15/06 02:59 PM
. * Gender-related differences in visceral perception in health and irritable bowel syndrome HeatherAdministrator   04/15/06 02:47 PM
. * Role of Stress, Infection, Inflammation in IBS HeatherAdministrator   03/16/06 12:22 PM
. * Pathophysiologic Mechanisms of IBS HeatherAdministrator   03/16/06 12:16 PM
. * Gum Chewing Stimulates Bowel Activity and Reduces Surgical Recovery Time HeatherAdministrator   03/04/06 01:04 PM
. * A bulging midriff roughly doubles women's chances of gallstone surgery HeatherAdministrator   03/04/06 12:56 PM
. * Lifestyle Factors and Symptoms of Gastro-oesophageal Reflux HeatherAdministrator   02/18/06 01:42 PM
. * IBS Patients Show Greater Brain Response to Subliminal Gut Stimuli HeatherAdministrator   02/18/06 01:32 PM
. * Discrepancies between Patient-Reported Outcomes and Clinician-Reported Outcomes in IBS HeatherAdministrator   02/01/06 12:15 PM
. * Distension technique influences the relationship between colonic and rectal hypersensitivity in IBS HeatherAdministrator   02/01/06 12:04 PM
. * Stability of Irritable Bowel Syndrome Using a Rome II-Based Classification HeatherAdministrator   01/18/06 04:27 PM
. * Digestive Woes May Keep the Overweight From Exercising HeatherAdministrator   01/18/06 04:00 PM
. * Possible role of nitric oxide in visceral hypersensitivity in patients with irritable bowel syndrome HeatherAdministrator   01/08/06 05:03 PM
. * A Survey on Patient Educational Needs in Irritable Bowel Syndrome HeatherAdministrator   01/08/06 04:53 PM
. * Gut motor function: immunological control in enteric infection and inflammation HeatherAdministrator   12/21/05 12:41 PM
. * Post-infectious Irritable Bowel Syndrome HeatherAdministrator   12/19/05 04:55 PM
. * Clinical Insights in IBS-C and Chronic Constipation HeatherAdministrator   12/08/05 12:37 PM
. * New Studies Gauge Knowledge, Attitudes and Preferences of Patients with Irritable Bowel Syndrome HeatherAdministrator   11/12/05 01:30 PM
. * The Genetics of Irritable Bowel Syndrome HeatherAdministrator   11/12/05 01:10 PM
. * Irritable Bowel Syndrome Study Shows That Targeted Antibiotics Lead To Long-lasting Improvement HeatherAdministrator   11/12/05 01:00 PM
. * Col