Help For Irritable Bowel Syndrome (IBS) - Education, Support, & Self Help for Irritable Bowel Syndrome
Heather & Company View Cart
Shop for IBSIBS Message BoardsIBS News & ReviewsStore Finder
Home
IBS Diet & Recipes
IBS Books
IBS Supplements
Yoga for IBS
Hypnosis for IBS
Tummy Teas
Get The IBS Diet Cheat Sheet
Get Trigger Foods, Safe Foods, Ten Commandments of Eating for IBS, More!

Enter First Name:

Enter Email:

We value your privacy


All Boards >> Irritable Bowel Syndrome Research Library

HeatherAdministrator

Reged: 12/09/02
Posts: 7677
Loc: Seattle, WA
All IBS subtypes have similar symptom severity
      09/05/14 03:50 PM

Symptoms, QOL did not differ between IBS subtypes

Rey de Castro NG. J Gastroenterol Hepatol. 2014;doi:10.1111/jgh.12704.
August 26, 2014

The three subtypes of irritable bowel syndrome did not significantly differ in terms of symptom severity and quality of life, according to recent study data.


“Traditionally, it has always been thought that patients with the diarrhea form of IBS tend to be more anxious,” Peter J. Whorwell, MD, PhD, professor of medicine and gastroenterology, Wythenshawe Hospital, United Kingdom, told Healio.com/Gastroenterology. “In addition, it has also been considered that the symptom profiles in the three subtypes are different. However, our study does not support these ideas and, in this large group of patients, there was very little to choose between them.”

Peter J. Whorwell

Whorwell and colleagues grouped 1,000 patients (79.6% female) with at least a 2-year history of pharmacologically resistant IBS by diarrhea (IBS-D; n=256), constipation (IBS-C; n=296) or mixed (IBS-M; n=448) bowel habit subtype. All were administered validated questionnaires to score symptom severity, somatization, quality of life (QOL) and anxiety or depression levels.

Researchers found no differences between groups for all tested factors (all P>.05), including symptom severity (P=.24), abdominal pain intensity (P=.31), anxiety (P=.16), depression (P=.08), QOL (P=.64), and noncolonic symptoms and somatization (P=.53). They did observe that symptom severity was slightly correlated with anxiety (P<.001), depression (P<.001) and QOL (P<.001), and moderately correlated to somatization (P<.001).

“Consequently, a patient should not necessarily be denied treatment, say for anxiety, just because they are constipated and that group is generally not thought to be as anxious as the diarrhea group,” said Whorwell. “The strength of this study is that it was done on a very large group of patients, therefore, the results are likely to be reliable.

“A possible drawback is that our patients tend to be quite severe as we are a referral center. However, when the more severe patients were excluded, the results still stayed much the same.”

Disclosure: Whorwell reports receiving research grants or honoraria from Danone, Almirall, Salix, Shire, Abbott and Norgine. The researchers report no other relevant financial disclosures.


http://www.healio.com/gastroenterology/irritable-bowel-syndrome/news/online/%7B15196ae9-899f-401f-86c0-52f6c6aa9612%7D/symptoms-qol-did-not-differ-between-ibs-subtypes

--------------------
Heather is the Administrator of the IBS Message Boards. She’s the author of Eating for IBS and The First Year: IBS, and the CEO of Heather's Tummy Care. Join her IBS Newsletter. Meet Heather on Facebook!

Post Extras Print Post   Remind Me!     Notify Moderator

Entire thread
Subject Posted by Posted on
* General IBS / Bowel Dysfunction HeatherAdministrator 07/14/03 01:56 PM
. * April is IBS Awareness Month: 10 recent advances in research, diagnostics HeatherAdministrator   04/16/18 02:05 PM
. * Bacteria can trigger stomach cancer HeatherAdministrator   08/25/17 04:11 PM
. * Fecal microbiota transplantation improved symptoms and quality of life in patients with IBS HeatherAdministrator   05/09/17 01:28 PM
. * Autism symptoms improve after fecal transplant, small study finds HeatherAdministrator   01/26/17 02:54 PM
. * Microbiota and arthritis: correlations or cause? HeatherAdministrator   02/19/16 01:09 PM
. * Takeda, Enterome to collaborate on microbiome-based drugs for IBD, IBS, other GI disorders HeatherAdministrator   01/11/16 03:21 PM
. * Risk factors for IBS in military include stress, infectious gastroenteritis HeatherAdministrator   01/11/16 03:19 PM
. * Risk Factors ID'd for Fecal Transplant Failure Heather<