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Reged: 12/09/02
Posts: 7677
Loc: Seattle, WA
Good Vibration(s) for Constipation?
      05/12/14 03:55 PM

Good Vibration(s) for Constipation?

Meeting Coverage
DDW Roundup: Constipation, Celiac Disease, Gastroparesis

Published: May 11, 2014
By Charles Bankhead, Staff Writer, MedPage Today

The study of the vibrating capsule involved 28 patients with chronic idiopathic constipation or constipation-subtype irritable bowel syndrome. The patients had a median age of 47 (range 19 to 65), and women accounted for all but three of the patients.

The capsule houses a tiny receiver and vibrating mechanism and is activated by an external transmitter. When activated, the device generates three pulses per minute in the colon, approximating normal peristalsis.

All patients discontinued use of laxatives for 2 weeks prior to enrollment. They swallowed two capsules per week for 2 weeks and kept daily records of bowel movements. The capsule was activated remotely 6 hours after intake.

All but two patients completed the study, said Yishai Ron, MD, of Tel-Aviv Sourasky Medical Center in Israel. The average number of spontaneous bowel movements increased from about two per week at baseline to almost four at the end of the study (P<0.0001). Three patients required rescue medication more than once during the run-in and study periods.

Two patients reported adverse events: one patient complained of abdominal pain, diarrhea, and flatulence and the other reported feeling muscle twitches in the abdominal wall.

"This was a safety trial mandated by the Israeli government," Ron told MedPage Today. "We showed that the device is safe. The clinical results are very favorable, but the study involved few patients and did not have a control group. The efficacy of the device must be evaluated in a randomized trial involving a larger number of patients."

Heather is the Administrator of the IBS Message Boards. She’s the author of Eating for IBS and The First Year: IBS, and the CEO of Heather's Tummy Care. Join her IBS Newsletter. Meet Heather on Facebook!

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