Help For Irritable Bowel Syndrome (IBS) - Education, Support, & Self Help for Irritable Bowel Syndrome
Heather & Company View Cart
Shop for IBSIBS Message BoardsIBS News & ReviewsStore Finder
Home
IBS Diet & Recipes
IBS Books
IBS Supplements
Yoga for IBS
Hypnosis for IBS
Tummy Teas
Get The IBS Diet Cheat Sheet
Get Trigger Foods, Safe Foods, Ten Commandments of Eating for IBS, More!

Enter First Name:

Enter Email:

We value your privacy


All Boards >> Irritable Bowel Syndrome Research Library

HeatherAdministrator

Reged: 12/09/02
Posts: 7677
Loc: Seattle, WA
Increased Anal Resting Pressure and Rectal Sensitivity in Crohn's Disease
      12/16/03 11:59 AM

Diseases of the Colon & Rectum 2003; 46(12):1685-1689

Increased Anal Resting Pressure and Rectal Sensitivity in Crohn's Disease

Peter Andersson, M.D., Ph.D. *; Gunnar Olaison, M.D., Ph.D. *; Olof Hallböök, M.D., Ph.D. *; Bernt Boeryd, M.D., Ph.D. †; Rune Sjödahl, M.D., Ph.D., F.R.C.S. *

PURPOSE:
Anal pathology occurs in 20 to 80 percent of patients with Crohn's disease in which abscesses, fistulas, and fissures account for considerable morbidity. The etiology is not clearly defined, but altered anorectal pressures may play a role. This study was designed to investigate anorectal physiologic conditions in patients with Crohn's disease compared with healthy controls.

METHODS:
Twenty patients with Crohn's disease located in the ileum (n = 9) or the colon (n = 11) without macroscopic proctitis or perianal disease were included. All were subjected to rectal examination, anorectal manometry, manovolumetry, and rectoscopy. Comparison was made with a reference group of 173 healthy controls of whom 128 underwent anorectal manometry, 29 manovolumetry, and 16 both examinations.

RESULTS:
Maximum resting pressure and resting pressure area were higher in patients than in controls (P = 0.017 and P = 0.011, respectively), whereas maximum squeeze pressure and squeeze pressure area were similar. Rectal sensitivity was increased in patients expressed as lower values both for volume and pressure for urge (P = 0.013 and P = 0.014, respectively) as well as maximum tolerable pressure (P = 0.025).

CONCLUSIONS:
This study demonstrates how patients with Crohn's disease without macroscopic proctitis have increased anal pressures in conjunction with increased rectal sensitivity. This may contribute to later development of anal pathology, because increased intra-anal pressures may compromise anal circulation, causing fissures, and also discharging of fecal matter into the perirectal tracts, which may have a role in infection and fistula development.

http://ipsapp003.lwwonline.com/content/getfile/164/91/18/abstract.htm


--------------------
Heather is the Administrator of the IBS Message Boards. She’s the author of Eating for IBS and The First Year: IBS, and the CEO of Heather's Tummy Care. Join her IBS Newsletter. Meet Heather on Facebook!

Post Extras Print Post   Remind Me!     Notify Moderator

Entire thread
Subject Posted by Posted on
* Inflammatory Bowel Disease HeatherAdministrator 07/14/03 01:51 PM
. * Dietary fiber associated with reduced Crohn's disease flares HeatherAdministrator   01/27/16 02:58 PM
. * Probiotics not superior for maintaining ulcerative colitis remission HeatherAdministrator   12/29/15 10:12 AM
. * Fecal transplant induces remission in active ulcerative colitis HeatherAdministrator   07/16/15 04:39 PM
. * 7 recent developments in Crohn's disease HeatherAdministrator   04/02/15 03:16 PM
. * Hormonal contraception improved menstrual-related IBD symptoms HeatherAdministrator   09/15/14 12:43 PM
. * Fecal lactoferrin differentiated IBD from IBS HeatherAdministrator   07/29/14 01:50 PM
. * Vitamin D and Cancer Risk in IBD HeatherAdministrator   07/15/14 02:53 PM
. * Self-assessment scale developed for patients with IBD-fatigue HeatherAdministrator   06/17/14 10:44 AM
. * Stool test distinguishes between IBD and IBS HeatherAdministrator   04/07/14 01:40 PM
. * Breathing exercises, meditation improved inflammatory markers, quality of life in IBD patients HeatherAdministrator   10/23/13 04:20 PM
. * Inflammatory Bowel Disease: Heat Waves Linked to Flares HeatherAdministrator   08/16/13 12:58 PM
. * Dietary changes may reduce effects of IBD HeatherAdministrator   06/27/13 05:43 PM
. * Genetic Clues May Help Unravel Cause of Crohn's HeatherAdministrator   11/02/12 12:59 PM
. * Inflammatory bowel, ulcerative colitis linked to intestinal fungi HeatherAdministrator   06/15/12 01:23 PM
. * Smoking makes Crohn's disease worse HeatherAdministrator   05/09/12 01:33 PM
. * Kids With Crohn’s Disease, Colitis Often Struggle at School HeatherAdministrator   04/23/12 01:22 PM
. * As Nations Develop, So May Bowel Disease HeatherAdministrator   01/09/12 12:01 PM
. * Loneliness Triggers Inflammatory Illnesses HeatherAdministrator   02/10/11 10:05 AM
. * Infants' antibiotic use tied to IBD risk HeatherAdministrator   11/03/10 01:42 PM
. * Olive Oil May Protect Against Ulcerative Colitis HeatherAdministrator   05/05/10 10:32 AM
. * Accutane may cause ulcerative colitis HeatherAdministrator   04/09/10 01:38 PM
. * Red meat may raise odds for ulcerative colitis, but oily fish could be protective HeatherAdministrator   03/11/10 01:22 PM
. * Inflammatory Bowel Disease and Irritable Bowel Syndrome: Separate or Unified? HeatherAdministrator   01/05/10 12:03 PM
. * Novel Compound Targets Mucosal Healing in Crohn's HeatherAdministrator   05/29/06 02:19 PM
. * Viagra May Help Crohn's Disease HeatherAdministrator   03/04/06 12:50 PM
. * Carbon Monoxide Eases Ulcerative Colitis Heather