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All Boards >> Irritable Bowel Syndrome Research Library

HeatherAdministrator

Reged: 12/09/02
Posts: 7655
Loc: Seattle, WA
Gender-related differences in visceral perception in health and irritable bowel syndrome
      04/15/06 02:47 PM

Gender-related differences in visceral perception in health and irritable bowel syndrome

Authors: KIM, HYUN SEO1; RHEE, POONG-LYUL; PARK, JUNGHO1; LEE, JUN HAENG1; KIM, YOUNG-HO1; KIM, JAE JUN1; RHEE, JONG CHUL1

Source: Journal of Gastroenterology and Hepatology, Volume 21, Number 2, February 2006, pp. 468-473(6)

Publisher:Blackwell Publishing

Irritable bowel syndrome (IBS) is more common in female subjects, and IBS patients generally exhibit reduced pain thresholds to rectal distension. The aim of the present paper was to determine gender-related differences in rectal perception in both healthy controls and IBS patients. Methods:

Fifty-nine IBS patients (age 20–65 years; 31 women, 28 men) with symptoms that fulfilled Rome-II criteria and 21 healthy controls (age 25–58 years; 11 women, 10 men) were recruited. Participants completed a questionnaire regarding bowel symptoms and psychological distress, and maximal tolerable pressures were evaluated via barostat tests. Results:

Although healthy women appear to have lower perception thresholds than men, significant gender differences in pain sensitivity were not detected. In addition, female patients with IBS also exhibited no enhanced colorectal perception, as compared with male IBS patients. Conclusions:

No gender differences in visceral perception were determined to exist between the healthy controls and the IBS patients. Therefore, the increased prevalence of IBS in women may be related to another set of pathophysiological factors, and not to gender-related differences in visceroperception.

http://www.ingentaconnect.com/content/bsc/jgh/2006/00000021/00000002/art00022;jsessionid=lp9l9jc1qwhm.henrietta

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Heather is the Administrator of the IBS Message Boards. She’s the author of Eating for IBS and The First Year: IBS, and the CEO of Heather's Tummy Care. Join her IBS Newsletter. Meet Heather on Facebook!

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