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HeatherAdministrator

Reged: 12/09/02
Posts: 7410
Loc: Seattle, WA
After Menopause, IBS Lessens in Women
      11/04/03 03:34 PM

After Menopause, Women Have Same Severity of Irritable Bowel Syndrome As Men
By Maggie Schwarz

BALTIMORE, MD -- October 15, 2003 -- The higher severity of irritable bowel syndrome (IBS) that women experience in comparison with men diminishes after menopause, according to a study of over 800 patients.

Researchers compared severity of IBS symptoms and IBS-specific impairment of quality of life in 826 women and men with the syndrome. Olafur S. Palsson, PsyD, University of North Carolina, Chapel Hill, North Carolina, United States, reported their findings here October 12th at the 68th Annual Scientific Meeting of the American College of Gastroenterology.

Dr. Palsson explained that women have more severe symptoms of IBS, they need more medications, and they go to the doctor more than men with IBS.

To determine whether this greater severity changes with age, the investigators obtained responses to a questionnaire from 638 women and 188 men who were diagnosed with functional bowel disorders and met Rome II criteria for IBS. Their ages ranged from 18 to 76 years (mean 51.9 years). The questionnaires included the IBS Severity Index and the IBS and poorer quality of life (QoL) questionnaire.

Results showed that after the age of 50, the severity of IBS symptoms in women and men is identical. Women in postmenopausal age groups (50+ years of age) had significantly less severity overall for IBS (P<0.0001), abdominal pain (p<0.0001) and bloating (P<0.001), and had higher quality of life scores on the QOL (P<0.05), compared to younger women.

Women younger than 50 had higher IBS severity scores compared to same-age men, but these differences disappeared in older age groups.

Overall IBS-QOL scores were not significantly different between the genders in any age group. However, analysis of the eight content subscales of the IBS-QOL, controlling for IBS severity differences, showed that women differed from men on two scales, with more impaired scores on body image (P<0.05) and food avoidance (P<0.01).

Dr. Palsson said the reduced severity of IBS symptoms after menopause is due to the drop in sex hormones, which are known to make IBS symptoms worse. "Three-quarters of women with IBS say their IBS symptoms are worse during menses," he said.

The research should help physicians take the effect of the menstrual cycle into account when treating women with IBS, Dr. Palsson said.

The study was supported by Novartis Pharmaceuticals Corporation.


[Study title: IBS Severity and Health-Related Quality of Life Improve With Age in Women But Not in Men. Abstract 81]

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Subject Posted by Posted on
* Gender / Hormones HeatherAdministrator 07/14/03 01:57 PM
. * Women, Hormones and IBS HeatherAdministrator   03/11/14 02:09 PM
. * Fennel is an effective herbal drug for menstrual pain HeatherAdministrator   08/27/13 11:29 AM
. * Constipation and Risk of Cardiovascular Disease among Postmenopausal Women HeatherAdministrator   08/03/11 03:58 PM
. * Differences in Gastrointestinal Symptoms According to Gender in Rome II Positive IBS and Dyspepsia HeatherAdministrator   03/11/10 01:51 PM
. * Gender-related differences in prepulse inhibition of startle in irritable bowel syndrome HeatherAdministrator   03/11/10 01:48 PM
. * No evidence of sex differences in heritability of irritable bowel syndrome HeatherAdministrator   03/31/08 11:36 AM
. * Acupuncture for the treatment of pain from a gender perspective. HeatherAdministrator   03/31/08 11:27 AM
. * The menstrual cycle and its effect on inflammatory bowel disease and irritable bowel syndrome HeatherAdministrator   11/07/07 02:35 PM
. * Irritable Bowel Syndrome Is More Common in Women Regardless of the Menstrual Phase HeatherAdministrator   11/07/07 02:31 PM
. * Pelvic floor dysfunction and IBS in patients with interstitial cystitis. HeatherAdministrator   10/10/07 12:33 PM
. * Women with IBS have abnormal pain modulation HeatherAdministrator   10/10/07 12:01 PM
. * Anxiety or Depression with IBS Affects More Women Than Men HeatherAdministrator   09/24/07 11:31 AM
. * Colonoscopies more difficult and painful for women and people with IBS HeatherAdministrator   09/24/07 11:22 AM
. * Role of gender and early childhood in constipation HeatherAdministrator   09/13/07 11:09 AM
. * Changes in Bowel Function: Pregnancy and the Puerperium HeatherAdministrator   03/01/07 01:39 PM
. * Drugs for gastrointestinal disorders in pregnant women. HeatherAdministrator   05/13/06 03:20 PM
. * Functional bowel disorders in patients with pelvic organ prolapse and incontinence HeatherAdministrator   12/08/05 12:10 PM
. * Sex specific alterations in autonomic function among patients with irritable bowel syndrome HeatherAdministrator   11/12/05 01:16 PM
. * Women With Interstitial Cystitis at Risk for Irritable Bowel Syndrome and Depression HeatherAdministrator   09/22/05 04:39 PM
. * Women and Men Perceive Pain Differently HeatherAdministrator   09/13/05 12:55 PM
. * Overlapping Conditions in Women With Irritable Bowel Syndrome HeatherAdministrator   04/24/05 03:58 PM
. * Bowel habit in irritable bowel syndrome in women: Defining an alternator HeatherAdministrator   04/10/05 06:18 PM
. * Recognition and treatment of irritable bowel syndrome among women with chronic pelvic pain HeatherAdministrator   03/28/05 12:18 PM
. * Irritable bowel syndrome, chronic pelvic inflammatory disease and endometriosis HeatherAdministrator   02/19/05 05:43 PM
. * A gene for diarrhoea-predominant IBS in women? HeatherAdministrator   11/28/04 02:21 PM
. * Autonomic Cardiovascular Responses Are Impaired in Women With Irritable Bowel Syndrome HeatherAdministrator   09/12/04 03:41 PM
. * Abdominal Bloating: Relation to Rectal Hypersensitivity and Menstrual Cycle HeatherAdministrator   06/27/04 01:55 PM
. * Catching Colon Cancer in Women Can Be Tough HeatherAdministrator   04/13/04 03:32 PM
. * Women More Sensitive to Pain Than Men HeatherAdministrator   04/13/04 03:31 PM
. * Gender Differences In Brain Response To IBS Pain HeatherAdministrator   11/18/03 03:32 PM
. * After Menopause, IBS Lessens in Women HeatherAdministrator   11/04/03 03:34 PM
. * Is hormone replacement therapy associated with an increased risk of irritable bowel syndrome? HeatherAdministrator   07/25/03 11:43 AM
. * Sleep disturbance influences gastrointestinal symptoms in women with irritable bowel syndrome. HeatherAdministrator   07/18/03 01:00 PM
. * Symptoms across the menstrual cycle in women with irritable bowel syndrome. HeatherAdministrator   07/18/03 12:58 PM
. * Does a physically active lifestyle improve symptoms in women with irritable bowel syndrome? HeatherAdministrator   07/18/03 12:54 PM
. * Relation between hysterectomy and the irritable bowel HeatherAdministrator   07/18/03 11:48 AM
. * Diagnosis and management of IBS, constipation, and diarrhea in pregnancy. HeatherAdministrator   07/18/03 11:47 AM
. * Physician perception of IBS management in women and men. HeatherAdministrator   07/15/03 06:38 PM
. * Gender issues in the management of IBD and IBS HeatherAdministrator   07/15/03 06:11 PM
. * Gender differences in gut transit HeatherAdministrator   07/15/03 06:07 PM
. * Bowel dysfunction in postmenopausal women. HeatherAdministrator   07/15/03 06:04 PM
. * Irritable Bowel Syndrome Worse During Periods HeatherAdministrator   07/14/03 03:25 PM
. * Sex-related differences in IBS patients: Central processing of visceral stimuli HeatherAdministrator   07/14/03 02:40 PM

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