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Reged: 12/09/02
Posts: 7389
Loc: Seattle, WA
Lifestyle Factors and Symptoms of Gastro-oesophageal Reflux
      02/18/06 01:42 PM

Alimentary Pharmacology & Therapeutics

Lifestyle Factors and Symptoms of Gastro-oesophageal reflux - A Population-Based Study

M. Nocon; J. Labenz; S.N. Willich

Background: Although the symptoms of gastro-oesophageal reflux disease are common in the general adult population, the aetiology of gastro-oesophageal reflux disease is still largely unknown. Lifestyle factors such as diet, body mass index, and smoking have been frequently suggested as possible risk factors.

Aim: In the present study, we investigated the relationship between various lifestyle factors and gastro-oesophageal reflux disease symptoms.

Methods: A total of 7124 subjects were interviewed as part of the German National Health Interview and Examination Survey, a representative sample of the general adult population. We examined a variety of possible risk factors, including age, gender, body mass index, smoking, alcohol consumption, sports and different foods. To investigate the association between lifestyle and symptoms, we used a multiple logistic regression model, including various gastro-oesophageal reflux disease patient characteristics.

Results: We found an association among those with reflux symptoms who were overweight and obese (odds ratio: 1.8, 95% confidence interval: 1.5-2.2; odds ratio: 2.6, 95% confidence interval: 2.2-3.2), respectively. Further risk factors included smoking and the frequent consumption of spirits, sweets, or white bread. Physical activity and the consumption of fruits seemed to have some protective effect.

Conclusions: Lifestyle factors - in particular overweight, obesity and smoking - were associated with increased reflux symptoms.

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