Help For Irritable Bowel Syndrome (IBS) - Education, Support, & Self Help for Irritable Bowel Syndrome
Heather & Company View Cart
Shop for IBSIBS Message BoardsIBS News & ReviewsStore Finder
IBS Diet & Recipes
IBS Books
IBS Supplements
Yoga for IBS
Hypnosis for IBS
Tummy Teas
Get The IBS Diet Cheat Sheet
Get Trigger Foods, Safe Foods, Ten Commandments of Eating for IBS, More!

Enter First Name:

Enter Email:

We value your privacy

All Boards >> Irritable Bowel Syndrome Research Library


Reged: 12/09/02
Posts: 7677
Loc: Seattle, WA
Dyspepsia and Irritable Bowel Syndrome After a Salmonella Gastroenteritis Outbreak
      07/24/05 02:48 PM

Gastroenterology - July 2005 • Volume 129 • Number 1

Dyspepsia and Irritable Bowel Syndrome After a Salmonella Gastroenteritis Outbreak: One-Year Follow-up Cohort Study

Background & Aims:

It has been reported that some patients develop functional digestive disorders, particularly irritable bowel syndrome (IBS), after acute gastroenteritis (AGE). However, the presence of dyspepsia has not been specifically addressed. We prospectively evaluated development of dyspepsia and IBS during a 1-year follow-up in a cohort of adult patients affected by a Salmonella enteritidis AGE outbreak.


Questionnaires were sent to 1878 potential participants at baseline and 3, 6, and 12 months; 677 had experienced a Salmonella enteritidis AGE on June 23, 2002, and 1201 had not (randomly selected controls, matched for village of residence, age, and sex). At 12 months, 271 patients and 335 controls returned the questionnaires. Data permitted the establishment of dyspepsia and IBS diagnosis by Rome II criteria. Results: Before the AGE outbreak, the prevalence of dyspepsia was similar in cases and controls (2.5% vs 3.8%); the prevalence of IBS was also similar (2.9% vs 2.3%). At 3, 6, and 12 months, the prevalence of both dyspepsia and IBS had increased significantly in exposed compared with unexposed subjects. Overlap between dyspepsia and IBS was frequent. At 1 year, the relative risk for development of dyspepsia was 5.2 (95% confidence interval, 2.7–9.8) and for IBS was 7.8 (95% confidence interval, 3.1–19.7). Prolonged abdominal pain and vomiting during AGE were positive predictors of dyspepsia. No predictive factors for IBS were found.


Salmonella gastroenteritis is a significant risk factor not only for IBS but also for dyspepsia; at 1 year of follow-up, 1 in 7 and 1 in 10 subjects developed dyspepsia or IBS, respectively.

Heather is the Administrator of the IBS Message Boards. She’s the author of Eating for IBS and The First Year: IBS, and the CEO of Heather's Tummy Care. Join her IBS Newsletter. Meet Heather on Facebook!

Post Extras Print Post   Remind Me!     Notify Moderator

Entire thread
Subject Posted by Posted on
* General IBS / Bowel Dysfunction HeatherAdministrator 07/14/03 01:56 PM
. * April is IBS Awareness Month: 10 recent advances in research, diagnostics HeatherAdministrator   04/16/18 02:05 PM
. * Bacteria can trigger stomach cancer HeatherAdministrator   08/25/17 04:11 PM
. * Fecal microbiota transplantation improved symptoms and quality of life in patients with IBS HeatherAdministrator   05/09/17 01:28 PM
. * Autism symptoms improve after fecal transplant, small study finds HeatherAdministrator   01/26/17 02:54 PM
. * Microbiota and arthritis: correlations or cause? HeatherAdministrator   02/19/16 01:09 PM
. * Takeda, Enterome to collaborate on microbiome-based drugs for IBD, IBS, other GI disorders HeatherAdministrator   01/11/16 03:21 PM
. * Risk factors for IBS in military include stress, infectious gastroenteritis HeatherAdministrator   01/11/16 03:19 PM
. * Risk Factors ID'd for Fecal Transplant Failure HeatherAdministrator   10/26/15 03:06 PM
. *