All Boards >> Irritable Bowel Syndrome Research Library

HeatherAdministrator

Reged: 12/09/02
Posts: 7679
Loc: Seattle, WA
Sleep and gastric function in irritable bowel syndrome: derailing the brain-gut axis
      07/18/03 12:42 PM

Gut. 1997 Sep;41(3):390-3.

Sleep and gastric function in irritable bowel syndrome: derailing the brain-gut axis.

Orr WC, Crowell MD, Lin B, Harnish MJ, Chen JD.

Thomas N. Lynn Institute for Healthcare Research, INTEGRIS Baptist Medical Center of Oklahoma, Oklahoma City 73112, USA.

BACKGROUND: Recently, several studies have shown an alteration in bowel function during sleep in patients with irritable bowel syndrome (IBS), and a recent study also suggests a remarkable increase in rapid eye movement (REM) sleep. These studies have suggested that an alteration in CNS function may play an important role in the pathogenesis of IBS. AIMS: To confirm the presence of an alteration in REM sleep in patients with IBS and to assess the relation between sleep and a non-invasive measure of gastric functioning, the electrogastrogram (EGG). PATIENTS: Ten patients with IBS and 10 age and sex matched normal volunteers. METHODS: All subjects slept one night in the sleep laboratory and underwent polysomnographic monitoring to determine sleep patterns, and recording of the EGG from surface electrodes. RESULTS: The IBS group had a notable and significant increase in the percentage and duration of REM sleep (p < 0.05). The control group had a decrease in the amplitude of the dominant EGG frequency from waking to non-REM sleep (p < 0.05), and a subsequent increase in the amplitude from non-REM to REM sleep (p < 0.05). No such changes were noted in the patients with IBS. CONCLUSIONS: Results confirmed the enhancement of REM sleep in patients with IBS and suggested an intrinsic alteration in autonomic and CNS functioning in patients with IBS.

PMID: 9378397 [PubMed - indexed for MEDLINE]
web page

--------------------
Heather is the Administrator of the IBS Message Boards. She’s the author of Eating for IBS and The First Year: IBS, and the CEO of Heather's Tummy Care. Join her IBS Newsletter. Meet Heather on Facebook!

Post Extras Print Post   Remind Me!     Notify Moderator

Entire thread
Subject Posted by Posted on
* Brain-Gut HeatherAdministrator 07/14/03 01:59 PM
. * There’s a ‘second brain’ in your gut — and it’s smarter than you think HeatherAdministrator   07/07/17 04:46 PM
. * Gut bacteria may play a role in regulating myelination in the brain's prefrontal cortex HeatherAdministrator   10/26/15 03:04 PM
. * Perceived stress higher among patients with IBS HeatherAdministrator   09/08/15 03:08 PM
. * How the Gut's Second Brain Influences Mood and Well-Being HeatherAdministrator   07/15/14 03:08 PM
. * Does bacteria connect the brain and the gut? HeatherAdministrator   09/27/13 11:44 AM
. * Women With IBS Show Changes In Their Brains HeatherAdministrator   07/28/10 11:01 AM
. * Brain-gut axis dysfunction in IBS HeatherAdministrator   03/16/10 11:27 AM
. * Olfactory and gustatory function in irritable bowel syndrome HeatherAdministrator   03/16/10 11:24 AM
. * Mind/Body psychological treatments for irritable bowel syndrome HeatherAdministrator   03/18/09 05:47 PM
. * Women With IBS Can't Switch Off Pain Response HeatherAdministrator   01/18/08 12:39 PM
. * Daily stress and gastrointestinal symptoms in women with irritable bowel syndrome HeatherAdministrator   12/06/07 04:41 PM
. * Colonic Hypersensitivity in IBS - Brain or Gut? HeatherAdministrator   09/13/07 12:04 PM
. * Stress, the Brain-Gut Axis, and IBS HeatherAdministrator   07/17/07 11:34 AM
. * The Effectiveness of Hypnotherapy in the Management of Irritable Bowel Syndrome HeatherAdministrator   10/26/06 10:16 AM
. * An international study of irritable bowel syndrome: Family relationships and mind-body attributions HeatherAdministrator   06/04/06 12:28 PM
. * A Neurobiology of Sensitivity? HeatherAdministrator   06/04/06 12:16 PM
. * Pathophysiology of IBS and Serotonin Signaling HeatherAdministrator   07/05/05 03:22 PM
. * Serotonin receptors and transporters — roles in normal and abnormal gastrointestinal motility HeatherAdministrator   11/08/04 04:38 PM
. * Alterations of sensori-motor functions of the digestive tract in the pathophysiology of IBS HeatherAdministrator   09/12/04 03:44 PM
. * Visceral Sensitivity Index: Development and Validation of a GI Symptom-Specific Anxiety Scale HeatherAdministrator   07/24/04 01:54 PM
. * Brain activity during distention of the descending colon in humans HeatherAdministrator   07/11/04 02:07 PM
. * Irritable bowel syndrome: a model of the brain-gut interactions HeatherAdministrator   05/25/04 12:28 PM
. * The human enteric nervous system HeatherAdministrator   05/11/04 07:10 PM
. * Images Show a Snub Really Is Like Kick in the Gut HeatherAdministrator   10/20/03 03:43 PM
. * The Brain-Gut Connection HeatherAdministrator   09/01/03 11:43 AM
. * The Neurobiology of Stress and Emotions, and IBS HeatherAdministrator   07/23/03 10:35 AM
. * Gut Feelings: The Surprising Link Between Mood and Digestion HeatherAdministrator   07/23/03 10:31 AM
. * Sleep and gastric function in irritable bowel syndrome: derailing the brain-gut axis HeatherAdministrator   07/18/03 12:42 PM
. * The autonomic nervous system in functional bowel disorders. HeatherAdministrator   07/18/03 12:40 PM
. * Regional cerebral activation in irritable bowel syndrome HeatherAdministrator   07/18/03 12:36 PM
. * Intestinal reactivity to words with emotional content and brain information processing in IBS HeatherAdministrator   07/18/03 12:35 PM
. * Perceptual hyperreactivity to auditory stimuli in patients with irritable bowel syndrome. HeatherAdministrator   07/18/03 12:33 PM
. * The gut as a neurological organ. HeatherAdministrator   07/18/03 12:28 PM
. * Brain research in functional gastrointestinal disorders. HeatherAdministrator   07/18/03 12:24 PM
. * The gut has a mind of its own HeatherAdministrator   07/14/03 04:07 PM

Extra information
0 registered and 0 anonymous users are browsing this forum.

Moderator:  Heather 



Permissions
      You cannot post until you login
      You cannot reply until you login
      HTML is enabled
      UBBCode is enabled

Thread views: 146199

Jump to

| Privacy statement Help for IBS Home

*
UBB.threads™ 6.2


Shop For IBS Here!