Help For Irritable Bowel Syndrome (IBS) - Education, Support, & Self Help for Irritable Bowel Syndrome
Heather & Company View Cart
Shop for IBSIBS Message BoardsIBS News & ReviewsStore Finder
Home
IBS Diet & Recipes
IBS Books
IBS Supplements
Yoga for IBS
Hypnosis for IBS
Tummy Teas
Get The IBS Diet Cheat Sheet
Get Trigger Foods, Safe Foods, Ten Commandments of Eating for IBS, More!

Enter First Name:

Enter Email:

We value your privacy


All Boards >> Irritable Bowel Syndrome Research Library

HeatherAdministrator

Reged: 12/09/02
Posts: 7677
Loc: Seattle, WA
Calcium polycarbophil compared with placebo in IBS
      07/15/03 11:10 PM

Note: Calcium polycarbophil is sold as Equalactin and Fibercon

Aliment Pharmacol Ther. 1993 Feb;7(1):87-92.

Calcium polycarbophil compared with placebo in irritable bowel syndrome.

Toskes PP, Connery KL, Ritchey TW.

Division of Gastroenterology, Hepatology and Nutrition, University of Florida College of Medicine, Gainesville 32610.

Calcium polycarbophil was compared with placebo in 23 patients with irritable bowel syndrome in a six-month, randomized double-blind crossover study. Patients received polycarbophil tablets at a dosage of 6 g/day (twelve 0.5-g tablets) or matching placebo tablets. At study end, among patients expressing a preference, 15 of 21 (71%) chose polycarbophil over placebo for relief of the symptoms of irritable bowel syndrome. Statistically significant differences favouring polycarbophil were found among the following patient subgroups: 15 (79%) of 19 with constipation: all six with alternating diarrhoea and constipation; 13 (87%) of 15 with bloating: and 11 (92%) of 12 with two or more symptoms. Polycarbophil was rated better than placebo in monthly global responses to therapy. Patient diary entries showed statistically significant improvement for ease of passage with polycarbophil. Polycarbophil was rated better than placebo for relief of nausea, pain, and bloating. The data suggest that calcium polycarbophil can benefit irritable bowel syndrome patients with constipation or alternating diarrhoea and constipation and may be particularly useful in patients with bloating as a major complaint.

Publication Types:
Clinical Trial
Randomized Controlled Trial

PMID: 8439642 [PubMed - indexed for MEDLINE]
web page

--------------------
Heather is the Administrator of the IBS Message Boards. She’s the author of Eating for IBS and The First Year: IBS, and the CEO of Heather's Tummy Care. Join her IBS Newsletter. Meet Heather on Facebook!

Post Extras Print Post   Remind Me!     Notify Moderator

Entire thread
Subject Posted by Posted on
* Diet HeatherAdministrator 07/14/03 01:58 PM
. * Diet, lifestyle outweigh genetic impact on gut microbiome HeatherAdministrator   03/19/18 02:39 PM
. * Fecal Profiling May Predict Dietary Response in IBS to FODMAPS Diet HeatherAdministrator   03/15/18 11:51 AM
. * Can a Western diet permanently alter the immune system? HeatherAdministrator   01/19/18 01:17 PM
. * High-fat diet leads to same intestinal inflammation as a virus HeatherAdministrator   06/23/17 04:25 PM
. * Gluten-free diet could increase cardiovascular risk in people without celiac disease HeatherAdministrator   05/09/17 01:35 PM
. * Gut microbiome profiles predict response to low FODMAP diet in IBS HeatherAdministrator   11/02/16 02:45 PM
. * Fructose malabsorption, symptom severity, IBS subtype predict response to low FODMAP diet HeatherAdministrator   06/27/16 02:44 PM
. * Fiber-Rich Diet May Boost Lung Function HeatherAdministrator   01/27/16 02:52 PM
. * 'Very limited evidence' to show FODMAPS diet helps IBS HeatherAdministrator