Help For Irritable Bowel Syndrome (IBS) - Education, Support, & Self Help for Irritable Bowel Syndrome
Heather & Company View Cart
Shop for IBSIBS Message BoardsIBS News & ReviewsStore Finder
IBS Diet & Recipes
IBS Books
IBS Supplements
Yoga for IBS
Hypnosis for IBS
Tummy Teas
Get The IBS Diet Cheat Sheet
Get Trigger Foods, Safe Foods, Ten Commandments of Eating for IBS, More!

Enter First Name:

Enter Email:

We value your privacy

All Boards >> Irritable Bowel Syndrome Research Library


Reged: 12/09/02
Posts: 7677
Loc: Seattle, WA
Glycemic Load, Carbohydrate Intake, and Risk of Colorectal Cancer in Women
      07/14/03 02:37 PM

Journal of the National Cancer Institute, Vol. 95, No. 12, 914-916, June 18, 2003
© 2003 Oxford University Press



Glycemic Load, Carbohydrate Intake, and Risk of Colorectal Cancer in Women: A Prospective Cohort Study
Paul D. Terry, Meera Jain, Anthony B. Miller, Geoffrey R. Howe, Thomas E. Rohan

Affiliations of authors: P. D. Terry, T. E. Rohan, Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY; M. Jain, Integrated Policy and Planning Division, Ontario Ministry of Health and Long-Term Care, and Department of Public Health Sciences, University of Toronto, Toronto, Canada; A. B. Miller, Department of Public Health Sciences, University of Toronto, and Division of Clinical Epidemiology, Deutsches Krebsforschungszentrum, Heidelberg, Germany; G. R. Howe, Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY.

Correspondence to: Paul D. Terry, Ph.D., M.P.H., National Institute of Environmental Health Sciences, Epidemiology Branch, P.O. Box 12233 MD A3–05, Research Triangle Park, NC 27709–2233 (e-mail:


Mounting evidence suggests that high circulating levels of insulin might be associated with increased colorectal cancer risk. The glycemic effects of diets high in refined starch may increase colorectal cancer risk by affecting insulin and/or insulin-like growth factor-I levels. We examined the association between dietary intake and colorectal cancer risk in a cohort of 49 124 women participating in a randomized, controlled trial of screening for breast cancer in Canada. Linkages to Canadian mortality and cancer databases yielded data on mortality and cancer incidence up to December 31, 2000. During an average 16.5 years of follow-up, we observed 616 incident cases of colorectal cancer (436 colon cancers, 180 rectal cancers). Rate ratios for colorectal cancer for the highest versus the lowest quintile level were 1.05 (95% confidence interval [CI] = 0.73 to 1.53; Ptrend = .94) for glycemic load, 1.01 (95% CI = 0.68 to 1.51; Ptrend = .66) for total carbohydrates, and 1.03 (95% CI = 0.73 to 1.44; Ptrend = .71) for total sugar. Our data do not support the hypothesis that diets high in glycemic load, carbohydrates, or sugar increase colorectal cancer risk.

web page

Heather is the Administrator of the IBS Message Boards. She’s the author of Eating for IBS and The First Year: IBS, and the CEO of Heather's Tummy Care. Join her IBS Newsletter. Meet Heather on Facebook!

Post Extras Print Post   Remind Me!     Notify Moderator

Entire thread
Subject Posted by Posted on
* Diet HeatherAdministrator 07/14/03 01:58 PM
. * Diet, lifestyle outweigh genetic impact on gut microbiome HeatherAdministrator   03/19/18 02:39 PM
. * Fecal Profiling May Predict Dietary Response in IBS to FODMAPS Diet HeatherAdministrator   03/15/18 11:51 AM
. * Can a Western diet permanently alter the immune system? HeatherAdministrator   01/19/18 01:17 PM
. * High-fat diet leads to same intestinal inflammation as a virus HeatherAdministrator   06/23/17 04:25 PM
. * Gluten-free diet could increase cardiovascular risk in people without celiac disease HeatherAdministrator   05/09/17 01:35 PM
. * Gut microbiome profiles predict response to low FODMAP diet in IBS HeatherAdministrator   11/02/16 02:45 PM
. * Fructose malabsorption, symptom severity, IBS subtype predict response to low FODMAP diet HeatherAdministrator   06/27/16 02:44 PM
. * Fiber-Rich Diet May Boost Lung Function