Fructose is not the cause of IBS and more ....
02/12/10 12:03 PM
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Syl
Reged: 03/13/05
Posts: 5499
Loc: SK, CANADA
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I believe they are related only through the brain-gut misconnection but the precise mechanisms need not be related. For example, methane gas produced by methogans in the colon is physiologically active and known to modulate GI motility in IBS-C. The higher the concentration of methane the more C (see references below). A similar thing does not occur in IBS-D or IBS-A. How methane might modulate serotonin or other neurotransmitters and hormones is unknown. So while IBS-D and IBS-C are related via the brain-gut misconnection they are unrelated via the physiological effects of methane on GI motility.
I don't believe I ever said fructose is the cause of IBS. It certainly isn't. Similarly caffeine, alcohol, fat, etc are not causes of IBS. The byproducts of fructose/fructans and other short chained carbohydrate (lactose, sorbitol, etc) fermentation in the colon are GI irritants and motility modulators like other GI irritants. Excess fructose is an IBS trigger. Since anywhere from 1/3 to 1/2 of IBSers exhibit fructose malabsorption then just like it makes sense to eliminate or reduce dairy, fat, etc it makes good sense to eliminate or reduce fructose/fructan consumption. And it make sense to include it on the EFI IBS trigger lists. 
Reference
Chatterjee, S., Park, S., Low, K., Kong, Y., & Pimentel, M. (2007). [url=http://www.ncbi.nlm.nih.gov/pubmed/17397408]The Degree of Breath Methane Production in IBS Correlates With the Severity of Constipation[/url, The American Journal of Gastroenterology, 102(4), 837-841
Hwang, L., Low, K., Khoshini, R., Melmed, G., Sahakian, A., Makhani, M., et al. (2010). Evaluating Breath Methane as a Diagnostic Test for Constipation-Predominant IBS . Digestive Diseases and Sciences, 55(2), 398-403
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