Fructose Malabsorption in IBS subtypes
11/19/09 03:22 PM
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Syl
Reged: 03/13/05
Posts: 5499
Loc: SK, CANADA
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Shawneric,
You may find this interesting.
A recent study by an outstanding Australian GI research group looked a fructose and lactose malabsorption across a variety of GI disorders. They found that fructose malabsorption occured with about equal amounts (48-55%) in IBS-C & IBS-D and about twice as often compared to IBS-A (24%).
Here is more detail
They looked at the occurence of fructose malabsorption, lactose malabsorption and ERBAL (Early Rise in Breath Hydrogen after Lactulose - that use to be the standard test for SIBO) across a variety of GI disorders and healthy individuals. Below is some data extracted from the more extensive Table 2 in the reference below.
Below are the percentages of the population in a variety of groups that tested positive for fructose malabsorption, lactose malabsorption, and ERBAL. The numbers in the brackets are the number of individuals in the group.
Healthy volunteers (71)
Fructose = 34%, Lactose = 18%, ERBAL = 39%
Crohn's disease (92)
Fructose = 61%, Lactose = 42%, ERBAL = 20%
Ulcerative colitis (56)
Fructose = 42%, Lactose = 40%, ERBAL = 25%
Coeliac disease – newly diagnosed (79)
Fructose = 34%, Lactose = 11%, ERBAL = 29%
Coeliac disease – treated (57)
Fructose = 33%, Lactose = 21%, ERBAL = 14%
All Functional GI disorders taken together (201)
Fructose = 45%, Lactose = 25%, ERBAL = 27%
Individual Function GI disorders
IBS-C (29)
Fructose = 55%, Lactose = 18%, ERBAL = 38%
IBS-D (44)
Fructose = 48%, Lactose = 18%, ERBAL = 23%
IBS-A (21)
Fructose = 24%, Lactose = 29%, ERBAL = 14%
Functional Bloating (24)
Fructose = 50%, Lactose = 38%, ERBAL = 25%
Functional Constipation (36)
Fructose = 44%, Lactose = 32%, ERBAL = 31%
Functional Diarrhea (28) )
Fructose = 59%, Lactose = 22%, ERBAL = 32%
Unspecified (19)
Fructose = 25%, Lactose = 29%, ERBAL = 25%
Reference
BARRETT, J. S., IRVING, P. M., SHEPHERD, S. J., MUIR, J. G., & GIBSON, P. R. (2009). Comparison of the prevalence of fructose and lactose malabsorption across chronic intestinal disorders . Alimentary Pharmacology & Therapeutics, 30(2), 165-174
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