Re: Looking at the full paper ...
05/31/12 07:31 AM
Very good question. I was wonder about that myself.
A previous study that cultured bacteria did aspiration from the jejunum using a catheter. They found only 4% of individuals with IBS had SIBO using concentration levels of more than 10^5 CFU/ml. In the paper you posted information about the authors state that when the concentration level was reduce to 10^3 CFU/ml then the jejunum aspirations showed a level of 43% not 4%. In the new study they used a level of 10^4 CFU/ml. Apparently there is still some debate about what level of bacteria should be used in the determination of SIBO. Also, in the previous study there were some methodological issues one of which was possible dilution of the fluid samples.
They are working on a GI capsule that can collect tissue samples. Perhaps the collection of small intestine fluid using a capsule might be possible too
Say Heather posted a link to the same study in a news release from Cedar Sina in the research library. It seems more balanced than the medical news today report.
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