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1. The data do not support an important role for SIBO according to commonly used clinical definitions, in IBS. However, mildly increased counts of small-bowel bacteria seem to be more common in IBS, and needs further investigation. Motility alterations could not reliably predict altered small-bowel bacterial flora.

2. Some propose that bacterial overgrowth is a common causative factor in the pathogenesis of symptoms in IBS; others point to evidence suggesting that the cause stems from more subtle qualitative changes in the colonic flora. Neither hypothesis has been confirmed, but the likelihood now seems remote that bacterial overgrowth will prove to be a major factor in what will eventually be defined as IBS.

3. In summary, we failed to detect a significant association between SIBO and IBS using either the LHBT (lactulost breath test) or the more specific 14C-D-xylose breath test. Our results suggest that studies employing the LHBT to diagnosis SIBO require further validation of the applied criteria. Additional studies are needed to clarify whether patients in different geographical locations have significant differing bacterial flora and whether these differences might be important in the expression of human illness.

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If you want a list of research references from reputable journals that you can read I would be happy to provide them to you. Also, check back through the posting on this web site and see how many people have been tested for SIBO and either tested negative or had no/negative results with SIBO treatment. Anyway - eventually, the research will make things clearer

Good luck with your SIBO tests. Tells us how it goes.

Reference
Posserud, I., P. O. Stotzer, E. S. Bjornsson, H. Abrahamsson, and M. Simren, 2007: Small intestinal bacterial overgrowth in patients with irritable bowel syndrome. Gut, 56, 802-808

Quigley, E. M. M., 2007: Bacteria: A New Player in Gastrointestinal Motility Disorders--Infections, Bacterial Overgrowth, and Probiotics. Gastroenterology Clinics of North America Gastrointestinal Motility Disorders, 36, 735-748.

Walters, B. and S. J. Vanner, 2005: Detection of Bacterial Overgrowth in IBS Using the Lactulose H2 Breath Test: Comparison with 14C-d-Xylose and Healthy Controls. The American Journal of Gastroenterology, 100, 1566-1570.

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