Help For Irritable Bowel Syndrome (IBS) - Education, Support, & Self Help for Irritable Bowel Syndrome   
Heather & Company View Cart  
Shop for IBSIBS Message BoardsIBS News & ReviewsStore Finder  
Home
IBS Diet & Recipes
IBS Books
IBS Supplements
Yoga for IBS
Hypnosis for IBS
Tummy Teas

All Boards >> Irritable Bowel Syndrome Research Library

HeatherAdministrator

Reged: 12/09/02
Posts: 7389
Loc: Seattle, WA
Pharmaceutical companies funding a number of studies into IBS in the UK
      05/25/04 12:00 PM

Researchers at The University of Nottingham, England have picked up almost £1 million in funding for a number of studies into a painful and distressing bowel condition that will affect up to one in 10 of the population at some time or another.

The team in the Division of Gastroenterology at the University, led by Professor Robin Spiller, are looking at various aspects of Irritable Bowel Syndrome (IBS) in a bid to increase our understanding of the mechanisms that underpin the condition and to develop new treatments for patients.

They have received £434,563 in funding from the drug company GlaxoSmithKline for a study examining evidence for inflammation of the gut in IBS patients. It is believed that some IBS patients may have a genetic predisposition to this kind of inflammation, which is usually associated with other bowel disorders such as Crohn’s disease and ulcerative colitis. Often these patients have to undergo many tests that turn out to be unnecessary before being correctly diagnosed with IBS.

Another aspect of the study is examining why as many as one in 10 people who suffer from severe Campylobacter food poisoning may go on to develop IBS. The study will be comparing people who have had a Campylobacter infection and developed IBS with those who have made a complete recovery to get a clearer idea of why some patients are at a greater risk.

Further research into inflammation in the gut in IBS may lead to new methods of identifying patients who would respond well to drugs not traditionally used for the treatment of bowel conditions but which are successfully used in the treatment of asthma.

The researchers have also received £172,914 from NovartisPharma and £360,000 from the Biotechnology and Biological Sciences Research Council to look at the role of serotonin in IBS. Serotonin is a ubiquitous signalling molecule used throughout the brain and gut to transmit impulses. The over-production of serotonin can cause vomiting and diarrhoea and part of the study is looking at whether serotonin levels can be altered by introducing different molecules into the system.

The researchers are seeking patients with IBS to take part in the study and anyone interested should contact Marguerite Richards on 0115 924 9924 ext 36804 or ext 44970 or by e-mail at marguerite.richards@nottingham.ac.uk

http://www.news-medical.net/view_article.asp?id=1439

--------------------
Heather is the Administrator of the IBS Message Boards. She’s the author of Eating for IBS and The First Year: IBS, and the CEO of Heather's Tummy Care. Join her IBS Newsletter. Meet Heather on Facebook!

Post Extras Print Post   Remind Me!     Notify Moderator

Entire thread
Subject Posted by Posted on
* Pharmaceutical HeatherAdministrator 07/14/03 01:50 PM
. * Medical Marijuana for Digestive Disorders: High Time to Prescribe? HeatherAdministrator   09/17/14 02:08 PM
. * Antibiotics Early in Life May Boost Obesity Risk HeatherAdministrator   08/18/14 03:13 PM
. * Antidepressants, psychological therapies effectively treated IBS HeatherAdministrator   07/15/14 02:49 PM
. * Proton pump inhibitor (acid reflux drugs) may cause heart disease HeatherAdministrator   09/23/13 03:22 PM
. * Older drugs are better than new ones HeatherAdministrator   06/13/13 02:00 PM
. * On Anti-Depressants? Some Raise Risk of C. Diff Infection HeatherAdministrator   05/13/13 05:51 PM
. * Heartburn drugs, NSAID painkillers use linked to IBS symptoms HeatherAdministrator   03/18/13 01:24 PM
. * FDA approves Linzess to treat certain cases of irritable bowel syndrome and constipation HeatherAdministrator   08/31/12 11:25 AM
. * 3-month FDA delay for potential IBS drug linaclotide HeatherAdministrator   04/23/12 01:45 PM
. * Latest FDA watch list includes GI drugs HeatherAdministrator   04/23/12 01:42 PM
. * Antibiotics that reduce gut bacteria linked to obesity HeatherAdministrator   05/06/11 12:25 PM
. * Rifaximin: a unique gastrointestinal-selective antibiotic for enteric diseases HeatherAdministrator   02/10/11 10:23 AM
. * Antacids increase risk of pneumonia HeatherAdministrator   01/14/11 04:35 PM
. * Editorial - Antibiotic Rifaximin (Xifaxan) Therapy for the Irritable Bowel Syndrome HeatherAdministrator   01/07/11 03:01 PM
. * Antiobiotic Rifaximin (Xifaxan) for Patients with Irritable Bowel Syndrome without Constipation HeatherAdministrator   01/07/11 02:59 PM
. * Proton Pump Inhibitor Drugs Tied to 80% Increase in Clostridium difficile Risk HeatherAdministrator   11/10/10 11:29 AM
. * Phase 3 clinical trials of linaclotide for IBS constipation HeatherAdministrator   10/13/10 02:44 PM
. * An over-the-counter drug for constipation offers superior symptom relief compared with a commonly used prescription agent HeatherAdministrator   07/16/10 03:17 PM
. * Benefit/risk ratio of Renzapride not sufficient to warrant further study in IBS-C HeatherAdministrator   04/07/10 01:32 PM
. * Adverse effects of drugs on small intestine and colon HeatherAdministrator   03/16/10 11:23 AM
. * Children's Belly Aches Don't Disappear With Antidepressant HeatherAdministrator   03/11/10 01:14 PM
. * Survey: Marijuana Use In Patients With IBS HeatherAdministrator   01/12/10 03:17 PM
. * FDA Approves Amitiza for IBS-C HeatherAdministrator   05/23/08 10:59 AM
. * Zelnorm no longer available except for emergency use HeatherAdministrator   04/11/08 12:05 PM
. * Clinical trial: phase 2 trial of lubiprostone for irritable bowel syndrome with constipation. HeatherAdministrator   02/15/08 11:20 AM
. * Role of Antibiotics vs Conventional Pharmacotherapy in Treating Symptoms of Irritable Bowel Syndrome HeatherAdministrator   01/03/08 04:45 PM
. * FDA permits the restricted use of Zelnorm HeatherAdministrator   08/09/07 11:41 AM
. * Antidepressant Therapy (Imipramine and Citalopram) for Irritable Bowel Syndrome HeatherAdministrator   06/20/07 01:56 PM
. * Neuromuscular Dysfunction and IBS: Clinical Implications for Drug Use HeatherAdministrator   02/04/07 04:30 PM
. * Enteric Bacteria and IBS HeatherAdministrator   11/26/06 02:51 PM
. * Rifaximin vs Placebo in Reducing Symptoms in Adults With IBS HeatherAdministrator   11/26/06 02:39 PM
. * Antibiotic Rifaximin Appears Safe and Effective for Irritable Bowel Syndrome HeatherAdministrator   10/26/06 10:29 AM
. * Citalopram (Celexa) Improves Symptoms of Irritable Bowel Syndrome HeatherAdministrator   10/14/06 12:57 PM
. * Marijuana eases chronic pain HeatherAdministrator   07/17/06 11:49 AM
. * Doctors group launches war on drug ads HeatherAdministrator   07/17/06 11:17 AM
. * New IBS drug in development in Japan HeatherAdministrator   07/05/06 05:13 PM
. * Marijuana and the gastrointestinal tract HeatherAdministrator   06/12/06 03:38 PM
. * Zelnorm Rejected Again in Europe HeatherAdministrator   04/02/06 03:25 PM
. * Antidepressants for IBS HeatherAdministrator   03/16/06 12:31 PM
. * Takeda Laxative Wins U.S. Approval for Adults HeatherAdministrator   02/18/06 01:36 PM
. * Cilansetron: ; Solvay Pharmaceuticals suspends registration activites in the U.S., HeatherAdministrator   01/18/06 04:15 PM
. * Hearburn Drugs Cause Diarrhea HeatherAdministrator   01/08/06 05:10 PM
. * Zelnorm fails to win EU panel backing HeatherAdministrator   12/21/05 11:25 AM
. * Non-steroidal anti-inflammatory drugs and gastrointestinal damage HeatherAdministrator   12/08/05 12:51 PM
. * Octreotide May Be Effective in Treatment of Nonconstipated IBS HeatherAdministrator   12/08/05 12:31 PM
. * Lack of Lasting Effectiveness of Miralax Laxative Treatment of Constipation. HeatherAdministrator   08/07/05 04:18 PM
. * Acute Hepatitis Associated With Lotronex HeatherAdministrator   07/24/05 02:37 PM
. * FDA revisions to safety labeling for Lotronex (alosetron ) HeatherAdministrator   05/22/05 06:46 PM
. * Clinical pharmacology of new motility promoting agents HeatherAdministrator   05/22/05 06:33 PM
. * Rationale for Using Serotonergic Agents to Treat Irritable Bowel Syndrome HeatherAdministrator   05/08/05 06:21 PM
. * Zelnorm Associated With Rare Cases of Severe Diarrhea, Ischemic Colitis HeatherAdministrator   04/24/05 03:48 PM
. * Clinical Response to Tricyclic Antidepressants in Functional Bowel Disorders not Related to Dosage HeatherAdministrator   03/28/05 01:32 PM
. * Efficacy and Safety of Alosetron in Men with Diarrhea-Predominant IBS HeatherAdministrator   02/19/05 05:56 PM
. * Irritable Bowel Syndrome Medications Side Effects Survey HeatherAdministrator   11/09/04 02:04 PM
. * On the Relationship Between Colon Ischemia, Irritable Bowel Syndrome, and Serotonergic Therapy of Irritable Bowel Syndrome HeatherAdministrator   10/24/04 07:10 PM
. * New Risk Information on Zelnorm for IBS for Women HeatherAdministrator   07/11/04 02:18 PM
. * The Relationship among Previous Antimicrobial Use and H. Pylori Infections HeatherAdministrator   06/27/04 01:33 PM
. * Therapeutic benefits of cannabis in migraine, fibromyalgia, irritable bowel syndrome HeatherAdministrator   06/04/04 03:54 PM
. * Pharmaceutical companies funding a number of studies into IBS in the UK HeatherAdministrator   05/25/04 12:00 PM
. * Irritable bowel syndrome helped by Paroxetine, a drug for depression HeatherAdministrator   05/10/04 02:15 PM
. * Fears cause low sales of Lotronex HeatherAdministrator   05/10/04 01:46 PM
. * Zelnorm Warning Issued by FDA HeatherAdministrator   05/10/04 01:01 PM
. * Renzapride Improves Symptoms in Constipation-Predominant Irritable Bowel Syndrome HeatherAdministrator   12/01/03 06:14 PM
. * Clinical Trial Guidelines for Pharmacological Treatment of IBS - Pharmacological Options HeatherAdministrator   12/01/03 05:55 PM
. * SOLVAY presses ahead with cilansetron, a new IBS drug HeatherAdministrator   11/18/03 03:43 PM
. * Measuring Treatment Effects in IBS Trials HeatherAdministrator   10/20/03 03:30 PM
. * FDA Orders Novartis To Pull Zelnorm Ads HeatherAdministrator   10/07/03 11:25 PM
. * Step-down dosage of PPI drugs for hearburn HeatherAdministrator   09/30/03 01:26 PM
. * Evaluation of drug treatment in irritable bowel syndrome HeatherAdministrator   09/30/03 12:52 PM
. * Pain Relievers and Intestinal Disorders HeatherAdministrator   09/16/03 04:20 PM
. * Hypersensitivity and hyperreactivity in IBS: opportunity for drug discovery HeatherAdministrator   07/18/03 12:39 PM
. * Antidepressants in the Treatment of IBS and Other Functional GI Disorders HeatherAdministrator   07/18/03 12:20 PM
. * Use of Antidepressants in the Treatment of IBS? HeatherAdministrator   07/14/03 03:58 PM
. * Combined use of SSRIs and NSAIDs increases the risk of GI adverse effects HeatherAdministrator   07/14/03 03:15 PM

Extra information
1 registered and 0 anonymous users are browsing this forum.

Moderator:  Heather 



Permissions
      You cannot post until you login
      You cannot reply until you login
      HTML is enabled
      UBBCode is enabled

Thread views: 230076

Jump to

| Privacy statement Help for IBS Home

*
UBB.threads™ 6.2



LEGAL DISCLAIMER - This website is not intended to replace the services of a physician, nor does it constitute a doctor-patient relationship. Information on this web site is provided for informational purposes only and is not a substitute for professional medical advice. You should not use the information on this web site for diagnosing or treating a medical or health condition. If you have or suspect you have an urgent medical problem, promptly contact your professional healthcare provider.

Any application of the recommendations in this website is at the reader's discretion. Heather Van Vorous, HelpForIBS.com, and Heather & Company for IBS, LLC are not liable for any direct or indirect claim, loss or damage resulting from use of this website and/or any web site(s) linked to/from it. Readers should consult their own physicians concerning the recommendations on these message boards.



Home | Shop for IBS | IBS Message Boards | IBS News & Reviews | IBS Support Groups
IBS Diet & Recipes | IBS Books | IBS Supplements | Yoga for IBS | Hypnosis for IBS
IBS Tummy Teas™ | Irritable Bowel Syndrome Glossary

About Us | IBS Links | Search this Site | Site Map | Shipping & Returns | Privacy & Security
Contact Us | For Doctors & Dietitians | Wholesale | Co-packing Services

© 1999-2009, Heather Van Vorous, HelpForIBS.com, Heather & Company for IBS, LLC.
All information & art is proprietary and may not be duplicated.
All rights reserved.

Legal & Medical Disclaimer

Website Design