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All Boards >> Irritable Bowel Syndrome Research Library

HeatherAdministrator

Reged: 12/09/02
Posts: 7639
Loc: Seattle, WA
Pharmaceutical companies funding a number of studies into IBS in the UK
† † † 05/25/04 12:00 PM

Researchers at The University of Nottingham, England have picked up almost £1 million in funding for a number of studies into a painful and distressing bowel condition that will affect up to one in 10 of the population at some time or another.

The team in the Division of Gastroenterology at the University, led by Professor Robin Spiller, are looking at various aspects of Irritable Bowel Syndrome (IBS) in a bid to increase our understanding of the mechanisms that underpin the condition and to develop new treatments for patients.

They have received £434,563 in funding from the drug company GlaxoSmithKline for a study examining evidence for inflammation of the gut in IBS patients. It is believed that some IBS patients may have a genetic predisposition to this kind of inflammation, which is usually associated with other bowel disorders such as Crohnís disease and ulcerative colitis. Often these patients have to undergo many tests that turn out to be unnecessary before being correctly diagnosed with IBS.

Another aspect of the study is examining why as many as one in 10 people who suffer from severe Campylobacter food poisoning may go on to develop IBS. The study will be comparing people who have had a Campylobacter infection and developed IBS with those who have made a complete recovery to get a clearer idea of why some patients are at a greater risk.

Further research into inflammation in the gut in IBS may lead to new methods of identifying patients who would respond well to drugs not traditionally used for the treatment of bowel conditions but which are successfully used in the treatment of asthma.

The researchers have also received £172,914 from NovartisPharma and £360,000 from the Biotechnology and Biological Sciences Research Council to look at the role of serotonin in IBS. Serotonin is a ubiquitous signalling molecule used throughout the brain and gut to transmit impulses. The over-production of serotonin can cause vomiting and diarrhoea and part of the study is looking at whether serotonin levels can be altered by introducing different molecules into the system.

The researchers are seeking patients with IBS to take part in the study and anyone interested should contact Marguerite Richards on 0115 924 9924 ext 36804 or ext 44970 or by e-mail at marguerite.richards@nottingham.ac.uk

http://www.news-medical.net/view_article.asp?id=1439

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Heather is the Administrator of the IBS Message Boards. Sheís the author of Eating for IBS and The First Year: IBS, and the CEO of Heather's Tummy Care. Join her IBS Newsletter. Meet Heather on Facebook!

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Entire thread
Subject Posted by Posted on
* Pharmaceutical HeatherAdministrator 07/14/03 01:50 PM
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. * Heartburn drugs, NSAID painkillers use linked to IBS symptoms HeatherAdministrator†† 03/18/13 01:24 PM
. * FDA approves Linzess to treat certain cases of irritable bowel syndrome and constipation HeatherAdministrator†† 08/31/12 11:25 AM
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. * Antacids increase risk of pneumonia HeatherAdministrator†† 01/14/11 04:35 PM
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. * Antiobiotic Rifaximin (Xifaxan) for Patients with Irritable Bowel Syndrome without Constipation HeatherAdministrator†† 01/07/11 02:59 PM
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. * Phase 3 clinical trials of linaclotide for IBS constipation HeatherAdministrator†† 10/13/10 02:44 PM
. * An over-the-counter drug for constipation offers superior symptom relief compared with a commonly used prescription agent HeatherAdministrator†† 07/16/10 03:17 PM
. * Benefit/risk ratio of Renzapride not sufficient to warrant further study in IBS-C HeatherAdministrator†† 04/07/10 01:32 PM
. * Adverse effects of drugs on small intestine and colon HeatherAdministrator†† 03/16/10 11:23 AM
. * Children's Belly Aches Don't Disappear With Antidepressant HeatherAdministrator†† 03/11/10 01:14 PM
. * Survey: Marijuana Use In Patients With IBS HeatherAdministrator†† 01/12/10 03:17 PM
. * FDA Approves Amitiza for IBS-C HeatherAdministrator†† 05/23/08 10:59 AM
. * Zelnorm no longer available except for emergency use HeatherAdministrator†† 04/11/08 12:05 PM
. * Clinical trial: phase 2 trial of lubiprostone for irritable bowel syndrome with constipation. HeatherAdministrator†† 02/15/08 11:20 AM
. * Role of Antibiotics vs Conventional Pharmacotherapy in Treating Symptoms of Irritable Bowel Syndrome HeatherAdministrator†† 01/03/08 04:45 PM
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. * Neuromuscular Dysfunction and IBS: Clinical Implications for Drug Use HeatherAdministrator†† 02/04/07 04:30 PM
. * Enteric Bacteria and IBS HeatherAdministrator†† 11/26/06 02:51 PM
. * Rifaximin vs Placebo in Reducing Symptoms in Adults With IBS HeatherAdministrator†† 11/26/06 02:39 PM
. * Antibiotic Rifaximin Appears Safe and Effective for Irritable Bowel Syndrome HeatherAdministrator†† 10/26/06 10:29 AM
. * Citalopram (Celexa) Improves Symptoms of Irritable Bowel Syndrome HeatherAdministrator†† 10/14/06 12:57 PM
. * Marijuana eases chronic pain HeatherAdministrator†† 07/17/06 11:49 AM
. * Doctors group launches war on drug ads HeatherAdministrator†† 07/17/06 11:17 AM
. * New IBS drug in development in Japan HeatherAdministrator†† 07/05/06 05:13 PM
. * Marijuana and the gastrointestinal tract HeatherAdministrator†† 06/12/06 03:38 PM
. * Zelnorm Rejected Again in Europe HeatherAdministrator†† 04/02/06 03:25 PM
. * Antidepressants for IBS HeatherAdministrator†† 03/16/06 12:31 PM
. * Takeda Laxative Wins U.S. Approval for Adults HeatherAdministrator†† 02/18/06 01:36 PM
. * Cilansetron: ; Solvay Pharmaceuticals suspends registration activites in the U.S., HeatherAdministrator†† 01/18/06 04:15 PM
. * Hearburn Drugs Cause Diarrhea HeatherAdministrator†† 01/08/06 05:10 PM
. * Zelnorm fails to win EU panel backing HeatherAdministrator†† 12/21/05 11:25 AM
. * Non-steroidal anti-inflammatory drugs and gastrointestinal damage HeatherAdministrator†† 12/08/05 12:51 PM
. * Octreotide May Be Effective in Treatment of Nonconstipated IBS HeatherAdministrator†† 12/08/05 12:31 PM
. * Lack of Lasting Effectiveness of Miralax Laxative Treatment of Constipation. HeatherAdministrator†† 08/07/05 04:18 PM
. * Acute Hepatitis Associated With Lotronex HeatherAdministrator†† 07/24/05 02:37 PM
. * FDA revisions to safety labeling for Lotronex (alosetron ) HeatherAdministrator†† 05/22/05 06:46 PM
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. * Efficacy and Safety of Alosetron in Men with Diarrhea-Predominant IBS HeatherAdministrator†† 02/19/05 05:56 PM
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. * New Risk Information on Zelnorm for IBS for Women HeatherAdministrator†† 07/11/04 02:18 PM
. * The Relationship among Previous Antimicrobial Use and H. Pylori Infections HeatherAdministrator†† 06/27/04 01:33 PM
. * Therapeutic benefits of cannabis in migraine, fibromyalgia, irritable bowel syndrome HeatherAdministrator†† 06/04/04 03:54 PM
. * Pharmaceutical companies funding a number of studies into IBS in the UK HeatherAdministrator†† 05/25/04 12:00 PM
. * Irritable bowel syndrome helped by Paroxetine, a drug for depression HeatherAdministrator†† 05/10/04 02:15 PM
. * Fears cause low sales of Lotronex HeatherAdministrator†† 05/10/04 01:46 PM
. * Zelnorm Warning Issued by FDA HeatherAdministrator†† 05/10/04 01:01 PM
. * Renzapride Improves Symptoms in Constipation-Predominant Irritable Bowel Syndrome HeatherAdministrator†† 12/01/03 06:14 PM
. * Clinical Trial Guidelines for Pharmacological Treatment of IBS - Pharmacological Options HeatherAdministrator†† 12/01/03 05:55 PM
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. * Measuring Treatment Effects in IBS Trials HeatherAdministrator†† 10/20/03 03:30 PM
. * FDA Orders Novartis To Pull Zelnorm Ads HeatherAdministrator†† 10/07/03 11:25 PM
. * Step-down dosage of PPI drugs for hearburn HeatherAdministrator†† 09/30/03 01:26 PM
. * Evaluation of drug treatment in irritable bowel syndrome HeatherAdministrator†† 09/30/03 12:52 PM
. * Pain Relievers and Intestinal Disorders HeatherAdministrator†† 09/16/03 04:20 PM
. * Hypersensitivity and hyperreactivity in IBS: opportunity for drug discovery HeatherAdministrator†† 07/18/03 12:39 PM
. * Antidepressants in the Treatment of IBS and Other Functional GI Disorders HeatherAdministrator†† 07/18/03 12:20 PM
. * Use of Antidepressants in the Treatment of IBS? HeatherAdministrator†† 07/14/03 03:58 PM
. * Combined use of SSRIs and NSAIDs increases the risk of GI adverse effects HeatherAdministrator†† 07/14/03 03:15 PM

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