Help For Irritable Bowel Syndrome (IBS) - Education, Support, & Self Help for Irritable Bowel Syndrome
Heather & Company View Cart
Shop for IBSIBS Message BoardsIBS News & ReviewsStore Finder
Home
IBS Diet & Recipes
IBS Books
IBS Supplements
Yoga for IBS
Hypnosis for IBS
Tummy Teas
Get The IBS Diet Cheat Sheet
Get Trigger Foods, Safe Foods, Ten Commandments of Eating for IBS, More!

Enter First Name:

Enter Email:

We value your privacy


All Boards >> Irritable Bowel Syndrome Research Library

HeatherAdministrator

Reged: 12/09/02
Posts: 7658
Loc: Seattle, WA
Relaxation intervention improves symptoms, may help treat IBS, IBD
      07/16/15 04:41 PM

Relaxation intervention improves symptoms, may help treat IBS, IBD

Kuo B, et al. PLOS ONE. 2015;doi:10.1371/journal.pone.0123861.

Participation in a relaxation response based mind-body group intervention was associated with improvements in disease-specific measures, trait anxiety and pain catastrophizing in patients with irritable bowel syndrome and inflammatory bowel disease, according to study findings.

The quality of life in patients with IBS and IBD is often significantly affected and influenced by stress and resiliency associated with these conditions.

Braden Kuo, MD, of the gastrointestinal unit at Massachusetts General Hospital, and colleagues sought to assess the impact of a 9-week relaxation-response based mind-body group intervention in patients with IBS (n = 19) and IBD (n = 29). The intervention focused on relaxation-response and the building of cognitive skills. They assessed symptom questionnaires and inflammatory markers before and after the intervention, and again at short-term follow-up.

Braden Kuo

Results indicated significant improvements in Pain Catastrophizing Scale scores post-intervention for IBD and at short-term follow-up for both IBS and IBD (from 10.7 at baseline to 5.0 at week-13, P = .02 for IBS; and from 14.8 to 9.6, P < .01 for IBD).

In addition, significant improvements were observed in Trait Anxiety scores from baseline to week-10 (from 39.0 to 33.7, P = .02 for IBS; and from 39.3 to 33.6, P < .01 for IBD). IBS-QOL scores increased from a mean of 67.1 at baseline to 74.8 at week-10 (P = .01) and to 80.6 at week-13 (P < .001); IBS Symptom Severity Index scores significantly decreased from a mean of 215 at baseline to 154 at week-5 (P < .01), 128 at week-10 (P < .001) and 147 at week-13 (P = .01); and IBD Questionnaire scores increased from a mean of 171 at baseline to 185 at week-10 (P < .01) and sustained at 184 at week-13 (P = .02).

Compared with 1,059 genes altered with the intervention among those with IBD, 119 genes were altered in those with IBS. Reduced expression of intervention response genes was significantly associated with inflammatory response, cell growth, proliferation and oxidative stress-related pathways in those with IBD. Significant upregulation of cell cycle regulation and DNA damage related gene sets were observed after the intervention in those with IBS.

Top focus molecules identified in IBS were TNF, AKT and NF-&#954;B; whereas inflammation (VEGF-C, NF-&#954;B) and cell cycle and proliferation (UBC, APP) associated genes emerged as top focus molecules in IBD, according to the researchers.

“Observed gene expression changes suggest that NF-&#954;B is a target focus molecule in both IBS and IBD — and that its regulation may contribute to counteracting the harmful effects of stress in both diseases. Larger, controlled studies are needed to confirm this preliminary finding,” Kuo and colleagues wrote.

Disclosure: The study was supported by a grant from the CDC and the International Foundation for Functional Gastrointestinal Diseases. The researchers report being a consultant for, receiving funding from and serving on the boards of Basis, Civitas Therapeutics, Furiex, Genova Diagnostics, Given Imaging, Lantheus Medical Imaging, Onyx Pharmaceuticals and Shire Human Genetic Therapies.

http://www.healio.com/gastroenterology/inflammatory-bowel-disease/news/online/%7B5cdf2f0b-7add-4e72-93d9-11218ce85f50%7D/relaxation-intervention-improves-symptoms-may-help-treat-ibs-ibd?utm_source=maestro&utm_medium=email&utm_campaign=gastroenterology%20news

--------------------
Heather is the Administrator of the IBS Message Boards. She’s the author of Eating for IBS and The First Year: IBS, and the CEO of Heather's Tummy Care. Join her IBS Newsletter. Meet Heather on Facebook!

Post Extras Print Post   Remind Me!     Notify Moderator

Entire thread
Subject Posted by Posted on
* Hypnosis / Hypnotherapy/Cognitive-Behavioral Therapy HeatherAdministrator 07/14/03 01:52 PM
. * Relaxation intervention improves symptoms, may help treat IBS, IBD HeatherAdministrator   07/16/15 04:41 PM
. * Is tummy trouble keeping your child out of school? It could be Irritable Bowel Syndrome. HeatherAdministrator   09/25/13 12:56 PM
. * Gut-directed hypnotherapy improves remission for Ulcerative Colitis HeatherAdministrator   09/11/13 11:24 AM
. * MP's support for pioneering IBS work by Michael Mahoney HeatherAdministrator   04/18/13 05:42 PM
. * Gut-directed group hypnotherapy improved quality of life in patients with IBS HeatherAdministrator   03/18/13 01:22 PM
. * Hypnosis effective in treating irritable bowels HeatherAdministrator   04/06/12 11:14 AM
. * Effects of Gut-Directed Hypnotherapy on IBS HeatherAdministrator   10/21/11 12:53 PM
. * Hypnosis as IBS health care quietly gains ground HeatherAdministrator   08/22/11 12:59 PM
. * Brain Imaging Illustrates How Meditation Reduces Pain HeatherAdministrator   04/20/11 03:16 PM
. * IBS Patient's Response To Hypnotherapy Can Be Predicted By Color Test HeatherAdministrator   12/09/10 11:10 AM
. * Even The Most Severe Symptoms Rapidly Relieved By Self-Directed Behavioral IBS Treatment HeatherAdministrator   05/13/10 10:47 AM
. * Rapid Response to Cognitive Behavior Therapy Predicts Treatment Outcome in Patients With Irritable Bowel Syndrome HeatherAdministrator   03/11/10 01:55 PM
. * Hypnotherapy for IBS - systematic review of patients shows long-lasting symptom relief HeatherAdministrator   11/24/09 01:09 PM
. * Hypnotherapy relieves more than just IBS symptoms HeatherAdministrator   05/28/09 01:31 PM
. * Using art to help understand the imagery of irritable bowel syndrome and its response to hypnotherapy HeatherAdministrator   03/05/09 02:52 PM
. * Hypnotherapy for IBS HeatherAdministrator   09/26/08 03:06 PM
. * Gastroenterologists are calling for hypnotherapy to be used more widely in treating IBS HeatherAdministrator   07/16/08 01:36 PM
. * Irritable Bowel Syndrome Audio Program Celebrates 10 Years of Success HeatherAdministrator   05/08/08 11:05 AM
. * Mind/Body psychological treatments for irritable bowel syndrome HeatherAdministrator   03/14/08 10:31 AM
. * Hypnosis and behavioral therapy ease irritable bowel syndrome HeatherAdministrator   02/14/08 02:15 PM
. * Gut-Directed Hypnotherapy Effective for Persistent IBS in Children HeatherAdministrator   12/06/07 03:09 PM
. * Short- and long-term benefit of relaxation training for irritable bowel syndrome HeatherAdministrator   10/10/07 12:46 PM
. * Hypnotherapy significantly helps IBS in both men and women - but differently HeatherAdministrator   09/24/07 11:41 AM
. * Cognitive Behavior Therapy Improves Symptoms in Irritable Bowel Syndrome HeatherAdministrator   09/13/07 12:32 PM
. * How Does Cognitive Behavior Therapy for Irritable Bowel Syndrome Work? HeatherAdministrator   08/08/07 01:12 PM
. * Hypnotherapy for IBS HeatherAdministrator   07/17/07 12:23 PM
. * Barriers to Mind-Body Medicine for IBS HeatherAdministrator   06/11/07 04:21 PM
. * Hypnotherapy Called a Cure for Pediatric Irritable Bowel Syndrome HeatherAdministrator   05/23/07 02:56 PM
. * A Comparative Analysis of Clinical Outcomes in the Refractive IBS Patient vs. the Newly Diagnosed HeatherAdministrator   01/21/07 03:35 PM
. * Hypnosis eases irritable bowel syndrome HeatherAdministrator   10/26/06 11:08 AM
. * Biofeedback for Functional Constipation HeatherAdministrator   07/05/06 05:46 PM
. * Mind-Body Treatments Ease Irritable Bowel HeatherAdministrator   05/29/06 01:43 PM
. * Gut-directed hypnotherapy upon health-related quality of life in patients with IBS HeatherAdministrator   05/13/06 12:34 PM
. * Dutch Study on IBS Hypnotherapy for Children HeatherAdministrator   04/02/06 03:46 PM
. * Hypnotherapy an effective treatment for IBS HeatherAdministrator   10/11/05 01:24 PM
. * Biofeedback Helpful in Outlet Dysfunction Constipation HeatherAdministrator   09/01/05 11:26 AM
. * Hypnotherapy could be a useful treatment for irritable bowel syndrome in primary care HeatherAdministrator   11/08/04 04:26 PM
. * Cognitive-behavioral therapy, hypnosis can help soothe irritable bowel syndrome HeatherAdministrator   08/08/04 02:41 PM
. * Hypnosis May Help Non-Responsive Irritable Bowel Syndrome Patients HeatherAdministrator   04/27/04 08:32 PM
. * Hypnosis treatment for severe irritable bowel syndrome HeatherAdministrator   04/27/04 04:59 PM
. * The growing case for hypnosis as adjunctive therapy for functional gastrointestinal disorders HeatherAdministrator   03/09/04 11:42 AM
. * Neuroscience looks at tthe remarkable effects of meditation on the brain HeatherAdministrator   12/16/03 11:48 AM
. * Long term benefits of hypnotherapy for irritable bowel syndrome. HeatherAdministrator   11/04/03 02:57 PM
. * Hypnosis for IBS HeatherAdministrator   10/20/03 03:27 PM
. * Cognitive-Behavioral Therapy Vs. Education and Desipramine Vs. Placebo HeatherAdministrator   09/16/03 03:52 PM
. * Long-term improvement in functional dyspepsia using hypnotherapy. HeatherAdministrator   07/18/03 12:46 PM
. * Hypnotherapy in irritable bowel syndrome: a large-scale audit HeatherAdministrator   07/15/03 06:27 PM
. * Overview of Published Research To Date on Hypnosis for IBS HeatherAdministrator   07/14/03 03:32 PM

Extra information
0 registered and 18 anonymous users are browsing this forum.

Moderator:  Heather 



Permissions
      You cannot post until you login
      You cannot reply until you login
      HTML is enabled
      UBBCode is enabled

Thread views: 250351

Jump to

| Privacy statement Help for IBS Home

*
UBB.threads™ 6.2

LEGAL DISCLAIMER - This website is not intended to replace the services of a physician, nor does it constitute a doctor-patient relationship. Information on this web site is provided for informational purposes only and is not a substitute for professional medical advice. You should not use the information on this web site for diagnosing or treating a medical or health condition. If you have or suspect you have an urgent medical problem, promptly contact your professional healthcare provider.

Any application of the recommendations in this website is at the reader's discretion. Heather Van Vorous, HelpForIBS.com, and Heather & Company for IBS, LLC are not liable for any direct or indirect claim, loss or damage resulting from use of this website and/or any web site(s) linked to/from it. Readers should consult their own physicians concerning the recommendations on these message boards.



Home | Shop for IBS | IBS Message Boards | IBS News & Reviews
IBS Diet & Recipes | IBS Books | IBS Supplements | Yoga for IBS | Hypnosis for IBS
IBS Tummy Teas | Irritable Bowel Syndrome Glossary

About Us | IBS Links | Search this Site | Site Map | Shipping & Returns | Privacy & Security
Contact Us | For Doctors & Dietitians | Wholesale | Co-packing Services

1999-2009, Heather Van Vorous, HelpForIBS.com, Heather & Company for IBS, LLC.
All information & art is proprietary and may not be duplicated.
All rights reserved.

Legal & Medical Disclaimer

Website Design