Help For Irritable Bowel Syndrome (IBS) - Education, Support, & Self Help for Irritable Bowel Syndrome
Heather & Company View Cart
Shop for IBSIBS Message BoardsIBS News & ReviewsStore Finder
Home
IBS Diet & Recipes
IBS Books
IBS Supplements
Yoga for IBS
Hypnosis for IBS
Tummy Teas
Get The IBS Diet Cheat Sheet
Get Trigger Foods, Safe Foods, Ten Commandments of Eating for IBS, More!

Enter First Name:

Enter Email:

We value your privacy


All Boards >> Irritable Bowel Syndrome Research Library

HeatherAdministrator

Reged: 12/09/02
Posts: 7677
Loc: Seattle, WA
Loneliness Triggers Inflammatory Illnesses
      02/10/11 10:05 AM

Loneliness Triggers Inflammatory Illnesses

LOS ANGELES—UCLA researchers reported today that chronically lonely people may be at a higher risk for certain types of inflammatory disease, because their feelings of social isolation trigger the activity of pro-inflammatory immune cells.

The research appears in the Feb. 7-11 issue of the journal Proceedings of the National Academy of Sciences.

In their analysis of 93 older adults, the researchers screened for gene function among different types of immune cells and found that genes originating from two particular cell types—plasmacytoid dendritic cells and monocytes—were overexpressed in chronically lonely individuals, compared with the remainder of the sample. These cell types produce an inflammatory response to tissue damage, and are part of the immune system's first line of defense, which produces an immediate inflammatory response to tissue damage.

It's this same inflammatory response that, over the long-term, can promote cardiovascular disease, cancer and neurodegeneration.

The report provides further evidence of how lifestyle and social environments can impact human health. In addition, the researchers suggest that evolutionarily ancient immune system cells may have developed a molecular sensitivity to our social environment in order to help defend us against socially transmitted pathogens.

The authors are Steven Cole, a member of the UCLA Cousins Center for Psychoneuroimmunology, an associate professor of medicine in the division of hematology–oncology at the David Geffen School of Medicine at UCLA, and a member of UCLA's Jonsson Comprehensive Cancer Center.

Other authors were Lewis C. Hawkley and Jesusa M. Arevalo of UCLA, and John T. Cacioppo of the University of Chicago.

The research was funded by the National Institutes of Health, the John D. and Catherine T. MacArthur Foundation, the Norman Cousins Center at UCLA, the John Templeton Foundation, and the James B. Pendleton Charitable Trust.

Source: University of California, Los Angeles (UCLA), Health Sciences

http://www.endonurse.com/news/2011/02/study-loneliness-triggers-inflammatory-illnesses.aspx

--------------------
Heather is the Administrator of the IBS Message Boards. She’s the author of Eating for IBS and The First Year: IBS, and the CEO of Heather's Tummy Care. Join her IBS Newsletter. Meet Heather on Facebook!

Post Extras Print Post   Remind Me!     Notify Moderator

Entire thread
Subject Posted by Posted on
* Inflammatory Bowel Disease HeatherAdministrator 07/14/03 01:51 PM
. * Dietary fiber associated with reduced Crohn's disease flares HeatherAdministrator   01/27/16 02:58 PM
. * Probiotics not superior for maintaining ulcerative colitis remission HeatherAdministrator   12/29/15 10:12 AM
. * Fecal transplant induces remission in active ulcerative colitis HeatherAdministrator   07/16/15 04:39 PM
. * 7 recent developments in Crohn's disease HeatherAdministrator   04/02/15 03:16 PM
. * Hormonal contraception improved menstrual-related IBD symptoms HeatherAdministrator   09/15/14 12:43 PM
. * Fecal lactoferrin differentiated IBD from IBS HeatherAdministrator   07/29/14 01:50 PM
. * Vitamin D and Cancer Risk in IBD HeatherAdministrator   07/15/14 02:53 PM
. * Self-assessment scale developed for patients with IBD-fatigue HeatherAdministrator   06/17/14 10:44 AM
. * Stool test distinguishes between IBD and IBS