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Heather

Reged: 12/09/02

Posts: 7080

Loc: Seattle, WA

Detection of Pulmonary Involvement in Inflammatory Bowel Disease
09/30/03 01:20 PM

Journal of Clinical Gastroenterology 2003; 37(4):292-298

Pulmonary Function Tests and High-Resolution CT in the Detection of Pulmonary Involvement in Inflammatory Bowel Disease

Necla Songur, MD; Yildiran Songur, MD; Meric Tuzun, MD; Ibrahim Dogan, MD; Dilek Tuzun, MD; Arzu Ensari, MD; Baki Hekimoglu, MD

Goals:
To assess the pulmonary involvement detected by pulmonary function tests (PFT) and high-resolution computed tomography (HRCT) in inflammatory bowel disease (IBD) patients and to investigate the relationship of the pulmonary abnormalities with respiratory symptoms and bowel disease activity.

Methods:
23 patients with ulcerative colitis, 13 patients with Crohn disease and 14 control subjects took part in this prospective, controlled study. In all patients, detailed clinical information was obtained and extent and activity of the bowel disease were established. Each patient underwent PFT and HRCT scanning.

Results:
A pulmonary function abnormality was present in 21 of 36 patients. In IBD patients, DLCO were significantly lower, but RV/TLC was significantly higher than those of controls. HRCT revealed air trapping, fibrosis, emphysema, bronchiectasis and alveolitis in 19 patients. One-third of the patients with PFT abnormality, and 42% of the patients with HRCT abnormality were respiratory symptom free. Approximately 80% of the patients with pulmonary involvement had active bowel disease.

Conclusions:
Pulmonary involvement is common in patients with IBD. A high degree of suspicion is necessary to detect the pulmonary abnormality in IBD, because considerably large proportions of the symptom free patients have abnormal findings on HRCT and PFT.

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Subject	Posted by	Posted on
Inflammatory Bowel Disease	Heather	07/14/03 01:51 PM
Genetic Clues May Help Unravel Cause of Crohn's	Heather	11/02/12 12:59 PM
Inflammatory bowel, ulcerative colitis linked to intestinal fungi	Heather	06/15/12 01:23 PM
Smoking makes Crohn's disease worse	Heather	05/09/12 01:33 PM
Kids With Crohn’s Disease, Colitis Often Struggle at School	Heather	04/23/12 01:22 PM
As Nations Develop, So May Bowel Disease	Heather	01/09/12 12:01 PM
Loneliness Triggers Inflammatory Illnesses	Heather	02/10/11 10:05 AM
Infants' antibiotic use tied to IBD risk	Heather	11/03/10 01:42 PM
Olive Oil May Protect Against Ulcerative Colitis	Heather	05/05/10 10:32 AM
Accutane may cause ulcerative colitis	Heather	04/09/10 01:38 PM
Red meat may raise odds for ulcerative colitis, but oily fish could be protective	Heather	03/11/10 01:22 PM
Inflammatory Bowel Disease and Irritable Bowel Syndrome: Separate or Unified?	Heather	01/05/10 12:03 PM
Novel Compound Targets Mucosal Healing in Crohn's	Heather	05/29/06 02:19 PM
Viagra May Help Crohn's Disease	Heather	03/04/06 12:50 PM
Carbon Monoxide Eases Ulcerative Colitis	Heather	01/18/06 04:12 PM
Colonoscopic Surveillance in Inflammatory Bowel Disease	Heather	10/11/05 01:33 PM
Oral Contraceptives and HRT a Risk Factor for Inflammatory Bowel Disease	Heather	09/13/05 01:22 PM
Cannabinoids Show Promise for Inflammatory Bowel Disease	Heather	09/01/05 11:23 AM
Differentiation of Inflammatory Bowel Disease and Irritable Bowel Syndrome	Heather	09/01/05 11:13 AM
The Clinical Epidemiology of Inflammatory Bowel Disease	Heather	08/22/05 04:45 PM
IBD Patients May Benefit From Folic Acid Supplementation	Heather	05/22/05 07:02 PM
Fish oil, soluble fiber, and antioxidants for corticosteroid sparing in ulcerative colitis	Heather	04/24/05 03:33 PM
Biotic Therapy Cuts Inflammation in Ulcerative Colitis	Heather	02/19/05 05:59 PM
Calming Crohn's Disease with Fish Oil and Antioxidants	Heather	01/07/05 04:55 PM
Probiotics Prove Just As Effective As a Popular Prescription Drug for Ulcerative Colitis	Heather	12/20/04 01:37 PM
Increased Incidence of Inflammatory Bowel Disease: The Price of the Decline of Infectious Burden?	Heather	11/28/04 02:58 PM
Diet May Influence Relapse in Ulcerative Colitis	Heather	10/24/04 07:50 PM
Parasite Therapy for Crohn's and Colitis?	Heather	08/08/04 03:00 PM
Pipeline Treatments, Novel Procedures Offer New Options for GI Diseases	Heather	06/04/04 06:41 PM
Faulty Gene for Crohn's Disease Found	Heather	04/13/04 03:19 PM
Data links Crohn's disease and antibiotics	Heather	02/24/04 02:07 PM
Elan Reports Successful Results of Antegren Trial for Crohn's Disease	Heather	02/10/04 01:30 PM
5-ASA Therapy for Inflammatory Bowel Disease No Bar to Colon Cancer	Heather	02/10/04 01:29 PM
Once-Daily Probiotic Treatment Maintains Remission in Ulcerative Colitis patients with Pouchitis	Heather	01/26/04 03:33 PM
Bone Disease and Intestinal Problems May Share a Common Cause	Heather	01/07/04 11:47 AM
Increased Anal Resting Pressure and Rectal Sensitivity in Crohn's Disease	Heather	12/16/03 11:59 AM
Environmental Factors May Play a Role in the Pathogenesis of IBD	Heather	12/01/03 05:56 PM
Colonoscopy Prep	Heather	10/17/03 12:05 PM
Detection of Pulmonary Involvement in Inflammatory Bowel Disease	Heather	09/30/03 01:20 PM
Indeterminate Colitis	Heather	09/16/03 03:33 PM
Familial Occurrence of Inflammatory Bowel Disease in Celiac Disease	Heather	09/16/03 03:30 PM
Bacteria in Milk Linked to Crohn's Disease and Possibly IBS	Heather	08/12/03 11:55 AM
Inflammatory Bowel Disease During Pregnancy.	Heather	07/15/03 06:20 PM
A study of the menopause, smoking, and contraception in women with Crohn's disease.	Heather	07/15/03 06:05 PM
Hormone replacement therapy prevents bone loss in patients with IBD	Heather	07/15/03 06:02 PM
Chemo Drug Improves Crohn's Symptoms	Heather	07/14/03 04:09 PM

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