Help For Irritable Bowel Syndrome (IBS) - Education, Support, & Self Help for Irritable Bowel Syndrome
Heather & Company View Cart
Shop for IBSIBS Message BoardsIBS News & ReviewsStore Finder
IBS Diet & Recipes
IBS Books
IBS Supplements
Yoga for IBS
Hypnosis for IBS
Tummy Teas
Get The IBS Diet Cheat Sheet
Get Trigger Foods, Safe Foods, Ten Commandments of Eating for IBS, More!

Enter First Name:

Enter Email:

We value your privacy

All Boards >> Irritable Bowel Syndrome Research Library


Reged: 12/09/02
Posts: 7672
Loc: Seattle, WA
Babies at Celiac Disease Risk Should Wait for Wheat
      06/20/05 04:24 PM

Babies at Celiac Disease Risk Should Wait for Wheat

Timing of first gluten in diet could help ward off the illness, study suggests.

By Serena Gordon
HealthDay Reporter

WEDNESDAY, May 18 (HealthDay News) -- New parents with a family history of either celiac disease or type 1 diabetes should be very careful about when they introduce wheat into their baby's diet, a new study suggests.

Researchers found that if wheat was introduced before 3 months of age or after 7 months, the risk of developing celiac disease was increased compared to babies who had their first taste of wheat when they were between 4 and 6 months old.

"Children fed wheat, barley or rye cereals in the first three months had a fivefold increased risk [for developing celiac disease] compared to children who didn't have those cereals until they were 4 to 6 months old," said study co-author Jill Norris, head of the section of epidemiology and community health at the University of Colorado at Denver and Health Sciences Center.

"Children who had cereals after 6 months had a small increase -- about a twofold increased risk," Norris said.

Norris and her colleagues published their findings in the May 18 issue of the Journal of the American Medical Association.

Celiac disease is an autoimmune disorder that causes the body to perceive gluten, a protein substance found in wheat, rye and barley, as harmful. As a result, the small intestine becomes damaged from the immune system's ongoing assault on gluten. Eventually, the small intestine becomes so damaged it can no longer process nutrients from other foods, and serious nutritional deficits can occur.

The disease is inherited and researchers have identified several genes associated with celiac disease autoimmunity. Not everyone with the gene defects, however, develops celiac disease.

All of the children in the study had known genetic defects that put them at greater risk of developing the disease, and Norris was quick to point out that because all of the children in her study were at increased risk to begin with, these findings do not apply to the general population of newborns.

Another important issue this study wasn't able to address is whether the early -- or late -- introduction of gluten into the diet contributed to the development of celiac disease, or simply accelerated the appearance of the illness, Norris said.

Between 1994 and 2004, Norris and her colleagues identified 1,560 newborns from the Denver area at increased risk of celiac disease, either because they carried a genetic mutation associated with celiac disease or had a first-degree relative with type 1 diabetes. The genetic defects associated with celiac disease are the same as those for type 1 diabetes, so a family history of type 1 diabetes is also a risk factor for celiac disease, Norris explained.

The investigators tracked health outcomes in each of the babies for an average of five years, interviewing parents, checking each child's blood for signs of celiac disease, and monitoring the youngsters' diets.

Fifty-one children developed celiac disease during the study, the researchers report. Children fed products containing gluten before they were 3 months old faced more than a fivefold increase in risk for the illness, while children first fed gluten products during their seventh month or later were at a slightly less than twofold increased risk of the disease, compared to babies fed gluten between 4 and 6 months.

Norris said the researchers weren't able to learn exactly why early and late wheat introduction was associated with the development of celiac disease, but she suspects that young babies' digestive systems are too immature to process gluten, a complex protein. This may cause some gluten to cross into the bloodstream, where the immune system would start to attack it.

And, in the case of those introduced to wheat later, Norris said they may simply be getting exposed to more gluten at once because older babies take in much larger amounts of food per meal than newborns.

While calling the trial a "welcome study, and the first to suggest that timing [of first wheat ingestion] may be a risk factor," Dr. Richard Farrell, an assistant professor of medicine at Harvard Medical School, said these findings must also be interpreted with caution.

"Only three infants actually exposed to gluten before four months developed celiac disease," noted Farrell, who wrote an accompanying editorial in the same issue of the journal. He said a much larger study needs to be done to corroborate the findings.

"As the editorial author said, this study leaves 'too many questions' unanswered," added Angela Kurtz, a pediatric nutritionist from New York University Medical Center.

Kurtz said previous research has shown a protective effect from breast milk, and she pointed out that this study did not address the potential effects breast-feeding might have on the development of celiac disease.

She recommends breast-feeding children exclusively until they reach 6 months of age. Then, when babies start eating solid food, Kurtz recommends starting with rice cereals, or fruits or vegetables.

"Hold off on wheat, rye and barley, and when you do introduce them, only give small amounts once a day," she said.

Both Norris and Farrell said the results of this study are far too preliminary to recommend any changes to the current feeding guidelines, which suggest beginning solid foods at 4 to 6 months of age.

More information

To learn more about celiac disease, visit the Celiac Disease Foundation.

SOURCES: Jill Norris, Ph.D., M.P.H., professor and head, epidemiology and community health, University of Colorado at Denver and Health Sciences Center, Denver; Richard Farrell, M.D., assistant professor, medicine, division of gasteroenterology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston; Angela Kurtz, M.S., R.D., pediatric nutritionist, New York University Medical Center, New York City; May 18, 2005, Journal of the American Medical Association

Heather is the Administrator of the IBS Message Boards. She’s the author of Eating for IBS and The First Year: IBS, and the CEO of Heather's Tummy Care. Join her IBS Newsletter. Meet Heather on Facebook!

Post Extras Print Post   Remind Me!     Notify Moderator

Entire thread
Subject Posted by Posted on
* Celiac / Gluten Intolerance HeatherAdministrator 07/14/03 01:59 PM
. * Relatives, spouses of celiac disease patients at risk for autoimmune disease HeatherAdministrator   07/09/15 03:39 PM
. * Children with silent celiac HeatherAdministrator   06/19/15 03:06 PM
. * Delays in gluten introduction, onset of celiac disease in at-risk infants linked HeatherAdministrator   10/07/14 02:23 PM
. * Evidence points to Monsanto Roundup as culprit in rise of gluten intolerance & IBS HeatherAdministrator   02/19/14 01:30 PM
. * New approach to celiac testing identifies more at risk HeatherAdministrator   08/30/13 12:11 PM
. * Is a Gluten-Free Diet Right for You? HeatherAdministrator   08/16/13 02:15 PM
. * FDA Defines ‘Gluten-free’ for Food Labels HeatherAdministrator   08/07/13 10:49 AM
. * Tooth damage may be a sign of celiac disease HeatherAdministrator   06/11/13 03:47 PM
. * The Gluten-Free Vegetarian — Not to Worry, the Food Options Are Plentiful HeatherAdministrator   04/17/13 12:01 PM
. * Gluten-Free, Whether You Need It or Not HeatherAdministrator   02/08/13 11:27 AM
. * Non-celiac gluten sensitivity less common than celiac disease HeatherAdministrator   10/31/12 11:32 AM
. * Most Cases of Non-Responsive Celiac Disease Due to Ongoing Gluten Consumption HeatherAdministrator   06/15/12 03:08 PM
. * The good and the bad of going gluten free HeatherAdministrator   06/15/12 01:18 PM
. * Weird!! Patients with Non-celiac Gluten Sensitivity Report More Symptoms than Those with Celiac Disease HeatherAdministrator   06/15/12 01:12 PM
. * Irritable Bowel Syndrome and Gluten Sensitivity Without Celiac Disease HeatherAdministrator   05/17/12 12:13 PM
. * Celiac disease is more common in older adults HeatherAdministrator   04/23/12 01:40 PM
. * Celiac Disease on the Rise in U.S. - from sanitation and hygiene? HeatherAdministrator   08/24/11 02:41 PM
. * Birth Month Seems to Be Linked to Celiac Disease HeatherAdministrator   05/09/11 11:50 AM
. * More People May Benefit From Going Gluten-Free HeatherAdministrator   05/09/11 11:44 AM
. * Gluten Causes Gastrointestinal Symptoms in Subjects Without Celiac Disease HeatherAdministrator   01/13/11 01:01 PM
. * Celiac Disease Is Increasing Worldwide HeatherAdministrator   08/04/10 11:57 AM
. * Gluten intolerance versus celiac disease HeatherAdministrator   04/14/10 10:27 AM
. * Celiac disease may strike elderly, too HeatherAdministrator   03/11/10 01:19 PM
. * Gene links to celiac disease may help drug search HeatherAdministrator   03/11/10 12:57 PM
. * Genetic links to celiac disease identified HeatherAdministrator   03/05/10 02:36 PM
. * People on gluten-free diets benefit from oats HeatherAdministrator   03/05/10 12:23 PM
. * Between Celiac Disease and Irritable Bowel Syndrome HeatherAdministrator   03/05/10 11:49 AM
. * Study confirms four-fold increase in wheat gluten disorder HeatherAdministrator   07/22/09 01:15 PM
. * Effect of gluten-free diet and co-morbidity of irritable bowel syndrome-type symptoms on celiac patients HeatherAdministrator   03/18/09 05:46 PM
. * Gluten-Free Diet in Patients Diagnosed With Diarrhea-Predominant Irritable Bowel Syndrome HeatherAdministrator   07/17/07 11:18 AM
. * Non-Toxic Wheat May Be an Answer to Celiac Disease HeatherAdministrator   10/28/05 11:57 AM
. * Babies at Celiac Disease Risk Should Wait for Wheat HeatherAdministrator   06/20/05 04:24 PM
. * Relief for celiac patients HeatherAdministrator   06/05/05 05:48 PM
. * Gastrointestinal Motility Disturbances in Celiac Disease. HeatherAdministrator   09/12/04 03:27 PM
. * Celiac Disease: Where We Are and Where We Are Going HeatherAdministrator   06/27/04 01:58 PM
. * No Link Apparent Between IBS and Celiac Disease HeatherAdministrator   04/27/04 09:01 PM
. * Oats Safe for Celiac in Children HeatherAdministrator   04/26/04 01:08 PM
. * Celiac disease is a risk factor for schizophrenia HeatherAdministrator   02/24/04 02:13 PM
. * Against the grain: The growing awareness of celiac sprue HeatherAdministrator   08/12/03 12:12 PM
. * Celiac disease: fertility and pregnancy. HeatherAdministrator   07/15/03 06:14 PM
. * Celiac disease and spontaneous abortion HeatherAdministrator   07/15/03 06:12 PM
. * Is it necessary to screen for celiac disease in postmenopausal osteoporotic women? HeatherAdministrator   07/15/03 06:09 PM
. * Celiac Disease: More Common Than You Think HeatherAdministrator   07/14/03 04:15 PM
. * High prevalence of small intestinal bacterial overgrowth in celiac patients HeatherAdministrator   07/14/03 03:04 PM

Extra information
0 registered and 19 anonymous users are browsing this forum.

Moderator:  Heather 

      You cannot post until you login
      You cannot reply until you login
      HTML is enabled
      UBBCode is enabled

Thread views: 116125

Jump to

| Privacy statement Help for IBS Home

UBB.threads™ 6.2

LEGAL DISCLAIMER - This website is not intended to replace the services of a physician, nor does it constitute a doctor-patient relationship. Information on this web site is provided for informational purposes only and is not a substitute for professional medical advice. You should not use the information on this web site for diagnosing or treating a medical or health condition. If you have or suspect you have an urgent medical problem, promptly contact your professional healthcare provider.

Any application of the recommendations in this website is at the reader's discretion. Heather Van Vorous,, and Heather & Company for IBS, LLC are not liable for any direct or indirect claim, loss or damage resulting from use of this website and/or any web site(s) linked to/from it. Readers should consult their own physicians concerning the recommendations on these message boards.

Home | Shop for IBS | IBS Message Boards | IBS News & Reviews
IBS Diet & Recipes | IBS Books | IBS Supplements | Yoga for IBS | Hypnosis for IBS
IBS Tummy Teas | Irritable Bowel Syndrome Glossary

About Us | IBS Links | Search this Site | Site Map | Shipping & Returns | Privacy & Security
Contact Us | For Doctors & Dietitians | Wholesale | Co-packing Services

1999-2009, Heather Van Vorous,, Heather & Company for IBS, LLC.
All information & art is proprietary and may not be duplicated.
All rights reserved.

Legal & Medical Disclaimer

Website Design