All Boards >> Hypnosis for Irritable Bowel Syndrome Discussions

shawneric

Reged: 01/30/03
Posts: 1738
Loc: Oregon
Re: Thanks
      04/08/03 09:06 AM

Kinoz, glad to hhear its helping.

I am going to keep posting some related serotonin info.

This is new and may have to do with gender differences, women have more serotonin in them then men.

1: Can J Gastroenterol 2003 Mar;17(3):191-6 Related Articles, Links

Sex differences of brain serotonin synthesis in patients with irritable bowel syndrome using a-[11C]methyl-l-tryptophan, positron emission tomography and statistical parametric mapping.

Nakai A, Kumakura Y, Boivin M, Rosa P, Diksic M, D'Souza D, Kersey K.

Fukui Medical University School of Medicine, Fukui, Japan.

BACKGROUND: Irritable bowel syndrome (IBS) is the most common functional bowel disorder and has a strong predominance in women. Recent data suggest that the brain may play an important role in the pathophysiology of IBS in the brain-gut axis. It is strongly suspected that serotonin (5-HT), a neurotransmitter found in the brain and gut, may be related to the pathophysiology of IBS. It is reported that a 5-HT3 antagonist is effective only in female patients with diarrhea-predominant IBS. OBJECTIVE: In the present study, 5-HT synthesis was measured using positron emission tomography, with a-[11C]methyl-l-tryptophan as the tracer, in patients with IBS. The aim of the present study was to compare 5-HT synthesis in the IBS patients with that in the controls, and to compare 5-HT synthesis between male and female IBS patients. METHODS: Six male and six female nonconstipated IBS patients were scanned. Age-matched healthy volunteers were scanned as controls. Eighty minute dynamic scans were performed. Functional 5-HT synthesis images were analyzed using statistical parametric mapping. RESULTS: 5-HT synthesis was greater only in the female IBS patients in the right medial temporal gyrus (multimodal sensory association cortex) compared with the female controls (P<0.001). CONCLUSIONS: The greater brain 5-HT synthesis in the female IBS patients than in the controls may be related to the pathological visceral pain processing of the IBS patients, a larger female predominance of the disorder, and the sex difference of the efficacy of the 5-HT3 antagonist in treatment.

PMID: 12677270 PubMed - in process

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My website on IBS is www.ibshealth.com


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Entire thread
Subject Posted by Posted on
* Serotonin Info KinOz 03/31/03 02:29 PM
. * Re: Serotonin Info Essence   04/01/03 05:06 PM
. * Re: Serotonin Info shawneric   04/01/03 07:50 AM
. * Re: Serotonin Info Andie   10/02/04 05:52 AM
. * Re: Serotonin Info shawneric   10/02/04 10:33 AM
. * Re: Serotonin Info shawneric   10/02/04 08:56 AM
. * seratonin link - hence bowel movements on mdma? jo1978   04/15/03 10:37 PM
. * Re: seratonin link - hence bowel movements on mdma? shawneric   04/16/03 08:22 AM
. * Re: Serotonin Info KinOz   04/01/03 10:01 PM
. * Re: Serotonin Info shawneric   04/02/03 06:41 AM
. * Re: Serotonin Info shawneric   04/03/03 09:33 AM
. * Re: Serotonin Info susaloh   04/09/03 03:55 AM
. * Re: Serotonin Info Galwae   04/10/03 11:57 AM
. * Re: Serotonin Info susaloh   04/10/03 11:40 PM
. * Re: Serotonin Info HeatherAdministrator   04/09/03 01:54 PM
. * Re: Serotonin Info - Answer to Heather's question susaloh   04/10/03 03:06 AM
. * Re: Serotonin Info shawneric   04/09/03 08:40 AM
. * Re: Serotonin Info -question for ShawnEric susaloh   04/11/03 09:30 AM
. * Re: Serotonin Info -question for ShawnEric shawneric   04/11/03 10:15 AM
. * Re: Serotonin Info -question for ShawnEric juniper   04/13/03 07:02 PM
. * Re: Serotonin Info -question for ShawnEric shawneric   04/14/03 08:25 AM
. * Re: Serotonin Info -question for ShawnEric looktostars   04/13/03 06:40 PM
. * Re: Serotonin Info -question for ShawnEric shawneric   04/14/03 08:29 AM
. * Sorry, but what's CBT? susaloh   04/11/03 10:41 AM
. * Cognitive Behavioral Therapy -nt- HeatherAdministrator   04/11/03 11:18 AM
. * Re: Cognitive Behavioral Therapy -nt- shawneric   04/11/03 12:06 PM
. * Re: Serotonin Info Essence   04/09/03 06:39 PM
. * Re: Serotonin Info chris123   04/09/03 06:33 AM
. * Re: Serotonin Info Essence   04/09/03 06:42 PM
. * Re: Serotonin Info HeatherAdministrator   04/09/03 01:49 PM
. * Re: Serotonin Info Essence   04/09/03 06:45 PM
. * Re: Serotonin Info HeatherAdministrator   04/10/03 10:25 AM
. * Re: Serotonin Info shawneric   04/11/03 09:02 AM
. * Re: Shawneric this may sound silly.. KinOz   04/04/03 02:25 PM
. * Re: Shawneric this may sound silly.. shawneric   04/05/03 09:14 AM
. * Re: Shawneric this may sound silly.. Snow for Sarala   04/06/03 09:45 AM
. * Re: Shawneric this may sound silly.. shawneric   04/05/03 10:09 AM
. * Re: Thanks KinOz   04/05/03 02:54 PM
. * Re: Thanks shawneric   04/08/03 09:06 AM
. * Re: bloating Essence   04/04/03 05:58 PM

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